New Drug Targets and Research Methods for Androgenetic Alopecia

February 2009 in “ Folia Pharmacologica Japonica ”

Hisaharu Yamada, Akiko Ikeda

androgenetic alopecia male pattern baldness hair growth cycle in vitro cell culture studies in vivo studies

TLDR The document concludes that more research is needed to create specific drugs for treating male pattern baldness.

This document summarizes a research paper from 2009 that explores the causes and potential treatments for androgenetic alopecia, or male pattern baldness. The paper discusses potential drug targets for treatment development, focusing on molecules involved in the hair growth cycle. It also discusses various methods for evaluating treatment effectiveness, including in vitro cell culture studies and in vivo studies using animals. The authors conclude that further research is needed to develop targeted drugs for the treatment of androgenetic alopecia.

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New Drug Targets and Research Methods for Androgenetic Alopecia

Research cited in this study

research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding

research Biology of the Hair Follicle: The Basics

research Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth

research Hair Growth Effect of Minoxidil

research Towards a Molecular Understanding of Hair Loss and Its Treatment

research Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways

research The Effects of Finasteride (Proscar) on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques (Macaca Arctoides)

research Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque

research Action of Topical Minoxidil in the Bald Stump-Tailed Macaque

research Growth of the Hair

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