Adipocyte Stem Cells Are Maintained by PDGFα Signaling in the Skin

April 2016 in “ Journal of Investigative Dermatology ”

Gilberto Gonzalez, Brett A. Shook, Brandon Holtrup, M. Rodeheffer, Valerie Horsley

Pdgfα signaling dermal adipose tissue dermal adipocyte stem cells hair follicle cycle adipocytes chronological aging depilation PI3K proliferation adipocyte differentiation hair growth PDGF alpha fat cells stem cells hair cycle aging hair removal phosphoinositide 3-kinase cell growth fat cell differentiation

Studysummary This study found that Pdgfα signaling is crucial for maintaining dermal adipose tissue in mice by initiating dermal adipocyte stem cell proliferation, with implications for age-related skin defects.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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