April 2016 in “Journal of Investigative Dermatology” Pdgfα signaling helps maintain fat cells in the skin and is important for hair growth, wound healing, and fighting infections.
182 citations,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
37 citations,
April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
12 citations,
August 2018 in “Journal of Dermatological Science” Scientists made stem cells that can grow hair by adding three specific factors to them.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.