December 2025 in “International Journal of Molecular Sciences” In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.
1 citations
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May 2017 in “Asian journal of medical sciences” This study found that dietary supplementation with collagen, chondroitin sulfate, low-molecular weight hyaluronic acid, Pycnogenol®, and coenzyme Q10 significantly improved skin hydration, elasticity, nail hardness, and hair condition in patients with age-related dermatological changes after 12 weeks.
October 2023 in “Dermatological reviews” In this study, exosomes isolated from fibroblast secretome and applied to the skin improved aging parameters like wrinkles and sagging over 12 weeks, suggesting these exosomes may enhance skincare formulations if their biological activity remains stable.
29 citations
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December 2021 in “Pharmaceutics” This review discusses the use of phospholipid soft vesicle carriers to improve the delivery and therapeutic outcomes of topical treatments for various skin conditions, but reports no new clinical results.
This study identified ten key magistral dermatological formulations, such as personalized trichological preparations and Kligman’s formula, which fill critical gaps unmet by standardized products, particularly in cases like pediatric scabies or autoimmune mucosal diseases, illustrating the role of compounding in precision medicine.
February 2024 in “Skin health and disease” This review reports that exosomes show potential in regenerative and cosmetic dermatology for applications like wound healing and hair loss mitigation, but their clinical use is currently limited by high costs, complex processing, and sparse clinical evidence.
153 citations
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October 2012 in “Skin Pharmacology and Physiology” This review discusses the use of caffeine in cosmetics for its fat-reducing, antioxidant, and hair growth properties, but reports no new research findings.
1 citations
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December 2025 in “Journal of Pharmacology and Experimental Therapeutics” Exosomes show promise in improving skin health and appearance.
October 2021 in “Interfaces Científicas” This study analyzed the nutritional composition of 75 nutricosmetic products, finding common ingredients like biotin and zinc, but emphasized the need for further research on their effectiveness for hair and nail health.
July 2026 in “Discover Food” This review critically examines scientific evidence on the health benefits of rosemary bioactives, finding potential in managing age-related diseases and skin aging conditions, and discusses their application in functional foods and aromatherapy, along with associated safety concerns.
2 citations
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January 2023 in “Pharmaceuticals” This review discusses factors affecting hair health, types of alopecia, and the potential of phytochemicals in managing hair loss but reports no new clinical results; it highlights the need for further studies.
August 2013 in “Han'gug saengmul gonghag hoeji/KSBB journal” This study found that callus extracts from apple 'Hirosaki' may improve collagen synthesis, hair follicle cell proliferation, and possess significant anti-inflammatory properties.
January 2026 in “ChemistrySelect” This study demonstrates that a newly developed bio-based, dual-phasic hair serum offers a sustainable and effective alternative to traditional silicone-based serums, enhancing hair cuticle integrity and consumer appeal while supporting environmentally friendly formulation design.
December 2023 in “Acta Facultatis Medicae Naissensis” This study reviews skin issues caused by COVID-19 and related measures, concluding that cosmeceuticals, positioned between cosmetics and pharmaceuticals, are widely recommended for managing these conditions unless they are severe.
January 2026 in “Cosmetics” In this study, yeast fermentation of Platycladus orientalis leaves was shown to enhance hair growth-promoting properties by affecting cell cycle phases in human dermal papilla cells, increasing growth factor VEGF, reducing inflammatory factor TGF-β1, and altering the expression of Wnt/β-catenin pathway-related genes.
1 citations
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November 2008 in “Gerontology” This article discusses the increasing use of lifestyle drugs by healthy individuals to alter appearance or slow aging and emphasizes the need for doctors to consider side effects and contraindications, but it reports no new clinical findings.
13 citations
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March 2013 in “International Journal of Cosmetic Science” This study reports that the tetrapeptide AcSDKP significantly promotes skin and hair health in vitro and ex vivo, suggesting it could be used cosmetically to counteract skin aging and hair loss.
August 2020 in “Research Square (Research Square)” This study found that physoxia improved hair follicle functions in co-cultures of dermal papilla cells and melanocytes by enhancing their biological activities and promoting hair growth and pigmentation.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In laboratory tests, this study evaluated several skin cream formulations and reported that formulation F6 showed superior stability and strong antioxidant potential, while all formulations were stable, of uniform consistency, had a suitable pH, and were non-irritant to the skin.
July 2025 in “International Journal of Pharmacognosy and Pharmaceutical Sciences” This review discusses acne's common triggers, challenges with conventional treatments, and the potential of alternative therapies to reduce side effects and enhance outcomes, highlighting an increasing interest in safer approaches due to the limitations of current topical options.
January 2026 in “Pharmaceutics” This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.
August 2026 in “Frontiers in Medicine” This article argues that esthetic dermatology could benefit from a more biologically informed approach through the integration of advanced biomarkers and imaging technologies, but cautions that many tools are not yet fully validated for clinical use.
September 2025 in “Medicine Today and Tomorrow” This analysis reported that exosomes and growth factors show promise in dermatology by activating skin regeneration processes, aiding conditions like atopic dermatitis and hyperpigmentation, though further research is needed to establish standardized protocols and assess long-term effects.
1 citations
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April 2023 in “Biomolecules” This study found that hair care products containing fermented papaya, fermented mangosteen, and caffeine significantly inhibited hair loss, increased hair density and thickness, and improved hair follicle structure in individuals with androgenic or diffuse alopecia over three months compared to placebo and caffeine controls.
46 citations
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October 2025 in “Journal of Nanobiotechnology” This review examines the potential of plant-derived exosome-like nanovesicles in dermatology, highlighting their bioactive properties and discussing challenges to their clinical application, but does not provide new clinical results.
6 citations
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June 2011 in “Daehan miyong hakoeji” The researchers reported that shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens showed potential as safe and effective natural ingredients for scalp care and scaling due to their antioxidative and antimicrobial properties.
1 citations
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July 2017 in “Journal of Pharmacognosy and Phytochemistry” This study identifies various phytochemicals in Thuja orientalis bark, potentially aiding its botanical identification and quality standardization.
1 citations
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January 2023 This article reviews the potential benefits of functional foods and natural products for skin and hair health but presents no new clinical findings.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review consolidates evidence on Croton tiglium's bioactive compounds and effects, discussing its potential uses in treatments like hair-growth formulations, yet emphasizes the significant safety challenges due to the plant's inherent toxicity.
5 citations
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January 2025 in “Pharmaceuticals” This review highlights the potential of Coffea arabica as an active ingredient in skincare, noting its bioactive compounds from leaves and beans show promising anticellulite, anti-inflammatory, antioxidant, and anti-aging properties, with unique phenolic concentrations in leaves offering enhanced skin benefits.