Plant-Derived Exosome-Like Nanovesicles: A Novel Therapeutic Perspective for Skin Diseases

    October 2025 in “ Journal of Nanobiotechnology ”
    Hui Liu, Tingru Dong, Can Dong … Wei Wang
    Studysummary This review examines the potential of plant-derived exosome-like nanovesicles in dermatology, highlighting their bioactive properties and discussing challenges to their clinical application, but does not provide new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 15

    1. Iris Germanica L. Rhizome-Derived Exosomes Ameliorated Dihydrotestosterone-Damaged Human Follicle Dermal Papilla Cells Through the Activation of Wnt/β-Catenin Pathway International Journal of Molecular Sciences · 2025
    2. A Pilot Randomized Controlled Trial Evaluating the Efficacy of an Exosome-Containing Plant Extract Formulation for Treating Male Alopecia Life · 2025
    3. Exosomes for Aesthetic Dermatology: A Comprehensive Literature Review and Update Journal of Cosmetic Dermatology · 2025
    4. Effects of Biomaterials Derived from Germinated Hemp Seeds on Stressed Hair Stem Cells and Immune Cells International Journal of Molecular Sciences · 2024
    5. Rose Stem Cell-Derived Exosomes for Hair Regeneration Enhancement via Noninvasive Electroporation in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2024
    6. Hesperidin from Orange Peel as a Promising Skincare Bioactive: An Overview International journal of molecular sciences · 2024
    7. The Skin and Inflamm-Aging Biology · 2023
    8. Ginseng-Derived Nanoparticles Induce Skin Cell Proliferation And Promote Wound Healing Journal of Ginseng Research · 2022
    9. Ashwagandha Seed Plant Exosome-Like Nanovesicles Promote In Vitro Cellular Regeneration of Human Dermal Hair Follicle, Endothelial and Fibroblast Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2022
    10. Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders Asian Journal of Pharmaceutical Sciences · 2022
    11. Effects of Exosomes from Adipose-Derived Stem Cells on Hair Loss: A Retrospective Analysis of 39 Patients Journal of cosmetic dermatology · 2022
    12. Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment Theranostics · 2022
    13. The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics Pharmacological research · 2021
    14. BMP2-Mediated PTEN Enhancement Promotes Differentiation of Hair Follicle Stem Cells by Inducing Autophagy Experimental cell research · 2019
    15. Exosome for Hair Regeneration: From Bench to Bedside Journal of the American Academy of Dermatology · 2019