TLDR TCM-derived nanovesicles show promise for wound healing and skin regeneration but need more research.
The document reviews the potential of traditional Chinese medicine-derived exosome-like nanovesicles (TCM-ELNVs) in wound repair and skin regeneration. TCM-ELNVs offer advantages over mammalian exosomes, such as better bioavailability, scalable production, and reduced zoonotic risks. They are rich in bioactive compounds, contributing to their anti-inflammatory, antioxidant, and wound-healing properties. The review highlights the processes of isolating, characterizing, and delivering TCM-ELNVs, emphasizing their stability and bioactivity. Despite their promise, the application of TCM-ELNVs in skin healing is still in early stages, with ongoing research needed to fully understand their mechanisms and optimize their therapeutic use.
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