Performance of Platycladus Orientalis Leaves Yeast Fermented Solution on Human Dermal Papilla Cells

    January 2026 in “ Cosmetics ”
    K. W. Chang, Lingjuan Liu, Xianqi Chen … Jing Wang
    Studysummary In this study, yeast fermentation of Platycladus orientalis leaves was shown to enhance hair growth-promoting properties by affecting cell cycle phases in human dermal papilla cells, increasing growth factor VEGF, reducing inflammatory factor TGF-β1, and altering the expression of Wnt/β-catenin pathway-related genes.
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    Research cited in this study 12

    1. Pathophysiological Mechanisms of Hair Follicle Regeneration and Potential Therapeutic Strategies Stem Cell Research & Therapy · 2025
    2. Screening of Anti-Hair Loss Plant Raw Materials Based on Reverse Network Pharmacology and Experimental Validation Current Issues in Molecular Biology · 2025
    3. Platycladus Orientalis Leaf Extract Promotes Hair Growth Via Non-Receptor Tyrosine Kinase ACK1 Activation Current Issues in Molecular Biology · 2024
    4. Comparative Analysis of Low-Dose Oral Minoxidil with Spironolactone Versus Finasteride or Dutasteride in Female Androgenetic Alopecia Management Archives of Dermatological Research · 2024
    5. ICP5249 Promotes Hair Growth by Activating the AMPK-Autophagy Signaling Pathway Journal of Microbiology and Biotechnology · 2024
    6. Effects of Camellia Oleifera Seed Shell Polyphenols and 1,3,6-Tri-O-Galloylglucose on Androgenic Alopecia via Inhibiting 5α-Reductase and Regulating Wnt/β-Catenin Pathway Fitoterapia · 2024
    7. Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth? A Review Comparing Their Therapeutic Efficacies, Phytochemical Components, and Modulatory Targets Molecules/Molecules online/Molecules annual · 2024
    8. Corrigendum: Water Extract of Cacumen Platycladi Promotes Hair Growth Through the Akt/GSK3β/β-Catenin Signaling Pathway Frontiers in Pharmacology · 2023
    9. The Burden of Alopecia Areata: A Scoping Review Focusing on Quality of Life, Mental Health, and Work Productivity Journal of the European Academy of Dermatology and Venereology · 2023
    10. Guava Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities Plants · 2022
    11. The Molecular Mechanism of Natural Products Activating Wnt/Beta-Catenin Signaling Pathway for Improving Hair Loss Life · 2022
    12. The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature British Journal of Dermatology · 1999