Studysummary This study found that supplementing raccoon dogs' diets with 0.25 g/kg Platycladus orientalis leaf extract improved growth performance and altered intestinal microbiota, but higher doses may have adverse effects. Our plain-language summary of this paper — not a Tressless recommendation.
The study on Platycladus orientalis leaf extract (PLE) in raccoon dogs found that a 0.25 g/kg PLE supplement significantly improved growth performance, fur quality, and feed efficiency, while also positively altering intestinal microbiota by reducing harmful bacteria like Prevotella copri. However, higher doses (0.50 g/kg and 1.00 g/kg) were associated with potential health risks, including liver damage and weakened heart function. Thus, while 0.25 g/kg PLE is beneficial, caution is needed with higher dosages.
February 2023 in “Frontiers in Pharmacology” This study found that the water extract of Cacumen Platycladi promotes hair growth and follicle development in mice, possibly by influencing dermal papilla cells through the Akt/GSK3β/β-Catenin signaling pathway.
10 citations
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November 2022 in “Protein & Cell” In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.
25 citations
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September 2020 in “Molecules” In this study, quercitrin was reported to promote hair growth and cell viability in cultured human dermal papilla cells by enhancing cellular energy metabolism and growth factor production via MAPK/CREB signaling.
24 citations
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January 2014 in “The American Journal of Chinese Medicine” This review compiles data on Platycladus orientalis leaves, noting their diverse pharmacological activities and advocating for more research to clarify their traditional blood-cooling and hematostatic uses.
54 citations
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January 2013 in “BMC Complementary and Alternative Medicine” In this study, topical application of Thuja orientalis extract promoted hair growth by inducing the anagen phase and increasing hair follicle size and number in telogenic mice.
