Phytochemical and Pharmacological Insights Into Croton Tiglium Linn: A Promising Herbal Remedy for Hair Growth and Beyond

Croton tiglium Linn., known for its medicinal properties in traditional medicine, is gaining attention for its potential in hair growth and other therapeutic applications. The plant contains bioactive compounds like tigliane diterpenoids, which can influence cell processes through protein kinase C (PKC) pathways, potentially promoting hair growth by enhancing microcirculation and antioxidative mechanisms. Despite its promising pharmacological activities, including anticancer and anti-inflammatory effects, the plant's toxicity, particularly from phorbol ester-rich seeds, poses challenges for safe use. This review emphasizes the need for detoxification and standardized formulations to harness its benefits while mitigating risks.