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The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.

A gene mutation in Lama3 is linked to a common type of hair loss.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.

Genes linked to wool fineness in sheep have been identified.

Certain fungi protect skin health, but changes can allow harmful fungi to cause serious infections, needing more research for treatment and control.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Melanoma characteristics vary by age, which could help doctors with diagnosis and prevention.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

The hair growth serum Trichosera® was effective in increasing hair regrowth and density and reducing hair fall without significant side effects.

Certain gene variations are linked to the thickness of cashmere goat hair.

Different types of skin on mice have unique chemical profiles related to how they grow and react to stress.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

A new mutation in the Hairless gene causes hair loss in two Pakistani families.

Some plants like Eclipta alba, Nardostachys jatamansi, and Rumex japonicus may help hair growth.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Lower SHBG levels may increase the risk of PCOS.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

FOXN1 gene variants cause low T cells and immune issues from birth.