72 citations
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June 2019 in “International Journal of Cosmetic Science” This review discusses the biological properties of 18β‐glycyrrhetinic acid derived from licorice root, highlighting its potential anti-inflammatory, antioxidant, and antimicrobial benefits in treating dermatological disorders, and reports no new experimental results.
26 citations
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December 2022 in “Future Journal of Pharmaceutical Sciences” This review discusses the use of terpenes and invasomes as permeation enhancers for transdermal drug delivery, focusing on their potential applications in pharmaceutical formulations, but it reports no new experimental results.
21 citations
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March 2022 in “Pharmaceuticals” This study found that Brigatinib-loaded nanospanlastics demonstrated enhanced cytotoxicity against lung cancer cells and improved drug stability and release compared to free Brigatinib.
14 citations
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September 2016 in “Journal of Photochemistry and Photobiology B Biology” This study observed that mercury-lamp irradiation may cause cleavage of disulfide bonds in keratins of white hair, leading to the formation of thiols in laboratory settings.
13 citations
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November 2021 in “Biomedicines” This review discusses the potential of plasma-activated liquid (PAL) in medical applications and highlights recent studies to inform researchers of its usage possibilities, but reports no new clinical findings.
10 citations
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February 2021 in “International Journal of Nanomedicine” This study found that a chitosan-decorated finasteride nanosystem exhibited satisfactory drug release and retention in rat skin, suggesting it could enhance topical delivery for androgenic alopecia treatment.
9 citations
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August 2024 in “Pharmacological Reviews” This review summarized advancements in intestinal lymphatic drug delivery, emphasizing the evolving understanding of lymphatics as active players in health and disease, which has led to innovative therapeutic strategies and enhanced pharmacokinetic outcomes via this delivery route.
5 citations
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April 2022 in “IntechOpen eBooks” This source describes the potential benefits of a nanoemulgel delivery system for enhancing the use of lipophilic drugs, improving patient compliance, and expanding treatment options for various conditions, including acne, arthritis-related inflammation, and Parkinson's disease, while also offering sunburn protection in cosmetic applications.
2 citations
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November 2025 in “Pharmaceutics” This study found that a CLSM-based approach could semi-quantitatively assess the transdermal penetration behavior of fluorescent dyes with different lipophilicities, offering a tool for early-stage screening of compound penetration.
2 citations
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December 2021 in “Pharmaceutics” This study demonstrated that a finasteride-loaded proniosome significantly enhanced transfollicular delivery and hair growth in mice without causing skin irritation, with effects comparable to a 2% minoxidil solution.
1 citations
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October 2023 in “International Journal of Women s Health” In this study, scalp hydration and pH levels were not significantly different between hijab-wearing and non-hijab-wearing women, suggesting that hijab-wearing does not impair scalp health if there's no history of underlying scalp or skin disorders and the hijab is not worn damp.
1 citations
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December 2022 in “Pharmaceutics” This study found that finasteride-loaded microemulsions using poloxamer 124 significantly enhanced skin penetration of the drug compared to a standard solution, primarily through targeting hair follicles via the transfollicular pathway, with intercluster, intercellular, and transcellular pathways contributing less.
August 2026 in “Skin Research and Technology” This study observed that among individuals with scalp seborrhoea, the scalp showed higher sebum levels, lower hydration, and compromised barrier function compared to other areas, and that a single shampoo application containing piroctone olamine significantly reduced sebum and oxidative stress markers.
This study found that radiofrequency microneedling significantly enhanced the absorption of topical triamcinolone acetonide, with insertion depth being more influential than RF energy levels.
January 2026 in “Medicine” This study found that elevated LDL-C levels increased the risk of developing androgenic alopecia, whereas HDL-C levels showed no significant effect.
December 2025 in “Sensors” In this review, recent advances in long-acting microneedle-based transdermal drug delivery systems are outlined, highlighting biodegradable polymers like PLA, PLGA, and PCL for sustained release and discussing challenges in clinical translation such as consistency in manufacturing and validating long-term efficacy and safety.
September 2025 in “Pharmaceutics” In this study, quercetin nanocrystals stabilized with glycyrrhizic acid were developed as a new treatment strategy for androgenetic alopecia, which significantly reduced DHT levels and improved hair regrowth in a mouse model, indicating synergistic potential for clinical application.
March 2025 in “Molecules” This study explored the in vitro skin penetration of two compounds from Tectona grandis leaf extract used for standardization and found that compound 1 penetrates more efficiently than compound 2, especially with a propylene glycol enhancer.
January 2025 in “International Journal of Research and Innovation in Applied Science” This study aimed to enhance the skin penetration of minoxidil by encapsulating it in glycerosomal vesicles, offering a potential improvement in transdermal drug delivery for treating androgenetic alopecia. Results of the investigation were not reported.
January 2024 in “Journal of cosmetic dermatology” This study found that Silibinin-loaded polymeric micelles significantly protected human hair from UV-B induced structural and chemical damage by preventing increases in roughness and reducing protein loss.
October 2022 in “Biomolecules” This study found that in male rats, chronic finasteride treatment reduced allopregnanolone levels, which, upon drug withdrawal, correlated with increased pro-inflammatory cytokines and altered neurotransmitter levels.
August 2021 in “Annales pharmaceutiques françaises” This study used computer simulations to evaluate the absorption of oral and topical finasteride for treating androgenetic alopecia, finding that topical applications resulted in lower plasma concentrations, suggesting potential viability as a treatment option.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.
48 citations
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January 2024 in “Frontiers in Pharmacology” This paper reviews strategies to enhance the effectiveness of topical drug delivery by addressing skin barrier challenges, optimizing drug delivery systems, and personalizing treatment approaches, highlighting both current advancements and limitations in the field.
45 citations
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March 2020 in “International Journal of Nanomedicine” This study found that nanoemulsion-based formulations, such as nanoemulgel and NFs, might serve as promising topical delivery systems for treating inflammatory diseases, potentially offering an alternative to traditional nonsteroidal anti-inflammatory drugs, which are associated with adverse effects.
39 citations
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August 2022 in “Pharmaceutics” This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.
35 citations
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November 2021 in “Journal of nanobiotechnology” This study reported that thymol-loaded nanoparticles showed promise as an antibiotic-free treatment for acne by effectively targeting the infection without disrupting healthy skin microbiota.
31 citations
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April 2020 in “Pharmaceutics” This study found that dexamethasone nanocrystals significantly increased drug penetration into skin compared to a traditional cream formulation, suggesting potential benefits for treating inflammatory skin conditions.
29 citations
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September 2020 in “Polymers” This study found that electrospun poly(ε-caprolactone)/poly(3-hydroxybutyrate) blend fibers demonstrated nanometric dimensions and promising properties for drug delivery, with curcumin release linked to fiber morphology and processing parameters.
26 citations
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January 2024 in “Gels” This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.