Evaluation of Skin Penetration of Fluorescent Dissolved Formulations Using Confocal Laser Scanning Microscopy

    November 2025 in “ Pharmaceutics ”
    Yoshihiro Oaku, Toyoyasu Kuwae, Takeshi Misono … Akinari Abe
    Studysummary This study found that a CLSM-based approach could semi-quantitatively assess the transdermal penetration behavior of fluorescent dyes with different lipophilicities, offering a tool for early-stage screening of compound penetration.
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    Research cited in this study 4

    1. Efficacy of Topical Minoxidil and Finasteride Association Compared to Monotherapy in Men With Androgenetic Alopecia: A Prospective, Randomized, Controlled, Assessor-Blinded, 3-Arm, Pilot Trial Journal of Cosmetic Dermatology · 2023
    2. Hydrogel-Forming Microneedles for Transdermal Drug Delivery Preprints.org · 2023
    3. Development and Skin Penetration Pathway Evaluation Using Confocal Laser Scanning Microscopy of Microemulsions for Dermal Delivery Enhancement of Finasteride Pharmaceutics · 2022
    4. Transdermal Permeation of Drugs in Various Animal Species Pharmaceutics · 2017