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research Skin permeability and transdermal delivery route of 50-nm indomethacin-loaded PLGA nanoparticles

39 citations , August 2017 in “Colloids and Surfaces B: Biointerfaces”

This study found that 50-nm PLGA nanoparticles delivered with iontophoresis enhanced skin permeation of indomethacin in rats more effectively than 100-nm nanoparticles, suggesting improved targeting of hair follicles.

research The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery

9 citations , January 2015 in “Springer eBooks”

This review discusses the enhancement of drug penetration through hair follicles and reports no new clinical results while noting the potential for future research on controlled drug release methods.

research Applications and limitations of lipid nanoparticles in dermal and transdermal drug delivery via the follicular route

95 citations , July 2015 in “European journal of pharmaceutics and biopharmaceutics”

This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.

research Omega 3 fatty acid-enriched nanoemulsion of thiocolchicoside for transdermal delivery: formulation, characterization and absorption studies

29 citations , June 2014 in “Drug delivery”

This study reported that nanoemulsions significantly improved the skin permeability of thiocolchicoside compared to its aqueous solution, suggesting they are effective carriers for its transdermal delivery.

research Nanocarrier Systems for Transdermal Drug Delivery

13 citations , October 2012 in “InTech eBooks”

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

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community Possible natural pp405 solution

in Research/Science 45 upvotes 1 year ago

Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

community New study on applying minox right after derma stamp

47 upvotes 1 month ago

Microneedling combined with minoxidil and finasteride improves hair growth in androgenetic alopecia, with effectiveness varying by severity. The study was retracted due to concerns about validity and potential AI-generated content.

community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

community 5mg cialis daily to deal with dutasteride

in Finasteride/Dutasteride 71 upvotes 9 months ago

Cialis is used to manage erectile dysfunction caused by finasteride and dutasteride, with mixed results. Some users report improvement, while others consider stopping the medication due to side effects.

community How do I not kill my partners cat while using minoxidil ?

in Minoxidil 156 upvotes 9 months ago

Minoxidil is toxic to cats, so users should wash hands after application and ensure it dries before pets are near. Some switch to oral minoxidil to avoid risks, while others use topical forms cautiously.

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