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Excess androgens may cause PCOS, not just be a symptom.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

Gene mutations can cause problems in male genital development.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Mutations in certain receptors can cause diseases and offer new treatment options.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Finasteride helps treat hair loss by blocking enzyme activity.

Finasteride side effects in young men may be linked to specific gene variations.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

No clear link between androgen receptor variation and hair loss, but more research needed.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.