June 2026 in “International Journal of Drug Delivery Technology” This study developed EGCG-loaded nanohydrogels using ethyl cellulose and polyvinyl alcohol to enhance the stability and delivery of the hydrophilic drug in aloe vera gel, optimizing encapsulation efficiency and drug release properties.
This study found that papaya seed extract gel accelerated hair length growth in rabbits, with the most effective concentration being 15%, though it did not significantly affect hair mass.
7 citations
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January 2022 in “Brazilian Journal of Biology” This study found that a shampoo formulation using mangabeira leaf extract without sodium lauryl sulfate showed promising antioxidant activity and improved foam quality.
August 2021 in “Majalah Obat Tradisional” This study found that a hair tonic formulated from green tea extract showed similar hair growth-promoting activity to 2% Minoxidil in rabbits, without causing skin irritation or bacterial contamination.
June 2026 in “Functional Foods in Health and Disease” This study found that water extract of olive leaf may enhance markers linked to epidermal and dermal stem cell activity and potentially improve skin aging, especially in individuals who do not exercise regularly.
8 citations
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September 2017 in “Journal of Natural Medicines” This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.
July 2025 in “Biotechnology and Bioprocess Engineering” This study found that Camellia japonica seed extract promotes hair growth by preventing premature cellular senescence and enhancing the activity of hair follicle stem cells in cases of pattern hair loss.
4 citations
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January 2011 This study found that Pleuropterus cilinervis extracts and animal milk fermented with Lactobacillus rhamnosus promoted hair growth in mice, suggesting potential applications in hair loss treatments.
December 2014 in “Research and Reviews: Journal of Pharmacology and Toxicological Studies” This study found that applying pet ether extract of Brassica oleracea to rats' skin promoted earlier and longer anagen phases in hair growth, outperforming 1% minoxidil.
December 2025 in “JOPS (Journal Of Pharmacy and Science)” This study reported that microemulsions containing celery ethanol extract significantly promoted rabbit hair growth, with the 10% extract formulation enhancing hair length by 2.7 times compared to a control, while showing good physical stability and no skin irritation.
1 citations
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January 2014 in “Journal of clinical & experimental dermatology research” This study suggests that the fresh leaf extracts of Naringi crenulata may promote hair growth in Wistar rats, potentially due to the presence of terpenoids and flavonoids.
April 2014 in “The FASEB Journal” This study found that Geranium Sibiricum L extract may promote hair growth by increasing cell proliferation and migration while modulating cytokine expression in human dermal papilla cells under stress conditions.
November 2025 in “Frontiers in Nutrition” Olive leaf extract may help reduce aging signs in postmenopausal women.
2 citations
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January 2020 in “BioMed Research International” This study found that Phaeodactylum tricornutum extract enhanced hair follicle cell proliferation, indicated by increased keratin and ERK1/2 signaling, suggesting its potential for hair care applications.
January 2026 in “Lumbung Farmasi Jurnal Ilmu Kefarmasian” This study found that a topical emulsion containing purified extracts of sidr leaves and roasted candlenut seeds significantly increased hair growth compared to the base and 2% minoxidil, potentially through their antioxidant and anti-inflammatory properties.
October 2024 in “AL-MIKRAJ Jurnal Studi Islam dan Humaniora (E-ISSN 2745-4584)” This study found that a hair tonic made with 30% ethanol extract from papaya fruit peel effectively promoted hair growth in guinea pigs, with results close to those of a positive control, and contains beneficial compounds like alkaloids and flavonoids.
1 citations
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February 2021 in “Cosmetics” This study found that the ethyl acetate extract of Fagraea berteroana fruits and its fraction FEAE-F0 promoted cell proliferation and modulated gene expression in hair follicle cells, suggesting potential for hair growth stimulation.
This study examined the use of Purwaceng extract in shampoo formulations, concluding that a specific formula (Sample F1) showed good stability and safety, suggesting its potential effectiveness for hair health issues like dandruff and hair loss.
15 citations
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August 2017 in “International Journal of Molecular Medicine” This study reported that Panax ginseng extract significantly inhibited DKK-1-induced catagen-like changes in human hair follicles by promoting cell proliferation and reducing apoptosis, suggesting it may help mitigate hair loss associated with DKK-1.
20 citations
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February 2009 in “Chemistry & Biodiversity” This study found that Ganoderma lucidum extracts showed weak 5alpha-reductase inhibition but significantly inhibited prostate cell proliferation and testosterone-driven prostate growth in rats, suggesting potential as an ingredient for treating androgen-induced diseases.
1 citations
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January 2022 in “Rasayan journal of Chemistry” This study found that ethanol and water extracts of Albizia saponaria bark significantly stimulated hair growth in male rabbits over 24 days.
2 citations
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December 2009 In a mouse study, topical application of certain herbal extract mixtures showed accelerated hair regrowth compared to controls, with noted increases in specific enzyme activities and growth factors that may aid alopecia treatment.
1 citations
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October 2023 in “Animals” This study found that supplementing raccoon dogs' diets with 0.25 g/kg Platycladus orientalis leaf extract improved growth performance and altered intestinal microbiota, but higher doses may have adverse effects.
July 2022 in “Asian Journal of Biochemistry, Genetics and Molecular Biology” This study found that Ageratum conyzoides showed antihyperglycemic and antilipidemic effects in diabetic rats, with significant changes in hematological and serum electrolyte parameters at 2000mg/kg.
4 citations
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November 2021 in “Pharmaceuticals” This study found that Paeonia lactiflora and Poria cocos extracts promoted hair regrowth in a mouse model of androgenetic alopecia, with similar effects observed to normal controls.
December 2022 in “Research Square (Research Square)” This study found that an extract from the herbal medicine Ophioglossum vulgatum Linn. showed potential hair growth promotion and increased ATP and catalase activity in cell assays, suggesting its use in treating alopecia.
February 2025 in “Eduvest - Journal Of Universal Studies” In a laboratory study on guinea pigs, Kepok banana peel extract serum at a 30% concentration showed promising effectiveness for hair growth, with results close to those of 5% minoxidil®, suggesting it could be a viable hair care alternative.
12 citations
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September 2014 in “Journal of Food Science and Nutrition” This study suggests that Platycarya strobilacea extract promotes hair growth in mice by enhancing stem cell factor expression, reducing mast cell numbers, and increasing cytokines associated with hair growth.
This study found that Polygonum multiflorum radix ethanol extract may promote melanin synthesis, potentially helping to turn gray hair back to black by enhancing antioxidant activity and increasing tyrosinase expression.
November 2025 in “Naukovij vìsnik veterinarnoï medicini” This study found that applying aqueous bay leaf extract to skin graft wounds in rabbits reduced inflammation and improved tissue regeneration, leading to enhanced healing compared to untreated controls, particularly in terms of collagen organization, fibrosis, and inflammation modulation over a 21-day period.