Formulation of Hair Tonic with Ethanol Extract of Papaya Fruit Skin (Carica Papaya L.) and Effectiveness Test on Hair Growth in Male Guinea Pigs (Cavia Porcellus)

The study investigates the potential of ethanol extract from papaya fruit skin (Carica papaya L.) as a hair tonic to promote hair growth. The research involved formulating hair tonics with varying concentrations (10%, 20%, 30%) of the extract and testing their effectiveness on male guinea pigs. The extract was found to contain beneficial compounds such as alkaloids, flavonoids, saponins, steroids, and glycosides. The 30% concentration hair tonic demonstrated the highest hair growth activity, with an average growth of 16.375 mm, closely matching the positive control's average of 16.782 mm. This suggests that the 30% ethanol extract formulation is effective in promoting hair growth.