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![The Inhibitory Effect of Scutellaria Baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia](/images/research/58865c87-ca3f-436b-b3b2-2bd46e762ce7/small/3414.jpg)
research The Inhibitory Effect of Scutellaria Baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia
Scutellaria baicalensis extract and baicalin may help prevent hair loss.
![The Roles of Wnt/β-Catenin Pathway in Tissue Development and Regenerative Medicine](/images/research/c441b698-792b-46e1-8bb5-3f496ca14340/small/19464.jpg)
research The Roles of Wnt/β-Catenin Pathway in Tissue Development and Regenerative Medicine
The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
![Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions](/images/research/fae5a9a1-a612-40f8-a864-e0942104363c/small/14663.jpg)
research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
![Conditioned Media Derived from Mesenchymal Stem Cell Cultures: The Next Generation for Regenerative Medicine](/images/research/b51f35a2-4a22-437b-8b11-61ef6dc1c949/small/15908.jpg)
research Conditioned Media Derived from Mesenchymal Stem Cell Cultures: The Next Generation for Regenerative Medicine
Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
![Emerging Nonmetabolic Functions of Skin Fat](/images/research/02ee4eac-e822-471a-afda-18cdd4dfa22d/small/19480.jpg)
research Emerging Nonmetabolic Functions of Skin Fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
![Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1](/images/research/7de5a316-1f7f-480b-9a73-a6046fe860ca/small/29670.jpg)
research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1
IGF-1 increases whisker growth in transgenic mice.
![Lrig1-Expressing Epidermal Progenitors Require SCD1 to Maintain the Dermal Papilla Niche](/images/research/e30819a0-1b43-4b00-a29e-e4671b7fcd59/small/31010.jpg)
research Lrig1-Expressing Epidermal Progenitors Require SCD1 to Maintain the Dermal Papilla Niche
Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.
![Interaction Between Stem Cell Factor and Endothelin-1: Effects on Melanogenesis in Human Skin Xenografts](/images/research/b990e167-7df3-4671-a1d1-44878c4b442e/small/19990.jpg)
research Interaction Between Stem Cell Factor and Endothelin-1: Effects on Melanogenesis in Human Skin Xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
![FGF Family: From Drug Development to Clinical Application](/images/research/c9f897a4-617a-4a24-a291-f96a9b0d8bde/small/19425.jpg)
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
![Protective Mechanism of Adipose-Derived Stem Cells in Remodeling of the Skin Stem Cell Niche During Photoaging](/images/research/7194f58e-ff1a-407d-8607-c5867ed9e173/small/19493.jpg)
research Protective Mechanism of Adipose-Derived Stem Cells in Remodeling of the Skin Stem Cell Niche During Photoaging
Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.
![Physiological and Retinoid-Induced Proliferations of Epidermis Basal Keratinocytes Are Differently Controlled](/images/research/9c36cf30-ec36-40a8-944d-473530d86e46/small/30948.jpg)
research Physiological and Retinoid-Induced Proliferations of Epidermis Basal Keratinocytes Are Differently Controlled
Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
![Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study](/images/research/2422502e-7d64-404e-8d0b-88579b3b5e62/small/3614.jpg)
research Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study
ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
![Modulation of Glucocorticoid Action and the Treatment of Type-2 Diabetes](/images/research/0c03c90d-dc7c-4aa4-b579-925514a217c5/small/15161.jpg)
research Modulation of Glucocorticoid Action and the Treatment of Type-2 Diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
![Expression and Roles of Steroidogenic Acute Regulatory (StAR) Protein in Non-Classical, Extra-Adrenal, and Extra-Gonadal Cells and Tissues](/images/research/3d9506a4-b6a1-4efb-89ad-37c1e5463146/small/14461.jpg)
research Expression and Roles of Steroidogenic Acute Regulatory (StAR) Protein in Non-Classical, Extra-Adrenal, and Extra-Gonadal Cells and Tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
![Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells](/images/research/aabf0b98-e7cb-4dc4-a584-8c7e86066902/small/4250.jpg)
research Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells
Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
![Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell-Conditioned Medium](/images/research/75452236-e0bb-451d-8b59-d70923ac678a/small/22897.jpg)
research Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell-Conditioned Medium
Using a special stem cell formula on the scalp once a month for six months helped people with hair loss grow more hair.
![Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization](/images/research/c4615f3c-20e1-456e-adcd-b6ab904ccfc5/small/19508.jpg)
research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization
FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
![Novel Effect of Sildenafil on Hair Growth](/images/research/a5357db6-08b8-4a68-896b-6d83a0952eae/small/22957.jpg)
research Novel Effect of Sildenafil on Hair Growth
Sildenafil, often used for erectile dysfunction, may help hair growth.
![Overexpression of Nanog in Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Dermal Papilla Cell Activity and Promotes Hair Follicle Regeneration](/images/research/81c84dc2-7c7a-44b9-bbd8-096862775681/small/4576.jpg)
research Overexpression of Nanog in Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Dermal Papilla Cell Activity and Promotes Hair Follicle Regeneration
Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.
![Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor](/images/research/b82073c2-9874-4f46-9f73-802e51715ec6/small/23067.jpg)
research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor
Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
![TR3 Is Preferentially Expressed by Bulge Epithelial Stem Cells in Human Hair Follicles](/images/research/c1ebdb62-0361-4785-a385-4afc68f8b583/small/25917.jpg)
research TR3 Is Preferentially Expressed by Bulge Epithelial Stem Cells in Human Hair Follicles
TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
![Morphogenetic Mechanisms in the Cyclic Regeneration of Hair Follicles and Deer Antlers from Stem Cells](/images/research/af9bd340-7fd0-4698-8c58-7e2344487931/small/34931.jpg)
research Morphogenetic Mechanisms in the Cyclic Regeneration of Hair Follicles and Deer Antlers from Stem Cells
Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.
![Effects of All-Trans Retinoic Acid on Goat Dermal Papilla Cells Cultured In Vitro](/images/research/92b66555-018e-4523-bb40-221b3be8cad9/small/22969.jpg)
research Effects of All-Trans Retinoic Acid on Goat Dermal Papilla Cells Cultured In Vitro
All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.
![Epidermal-Dermal Coupled Spheroids Are Important for Tissue Pattern Regeneration in Reconstituted Skin Explant Cultures](/images/research/84c7dd14-ca3a-4d7c-a48e-1f902b64d68c/small/34293.jpg)
research Epidermal-Dermal Coupled Spheroids Are Important for Tissue Pattern Regeneration in Reconstituted Skin Explant Cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
![Modulating the Stem Cell Niche for Tissue Regeneration](/images/research/72e0ffd3-8635-4ae7-8b4e-2567ba1da7b2/small/19726.jpg)
research Modulating the Stem Cell Niche for Tissue Regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
![Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition](/images/research/9cf7c66b-3dfe-4603-a199-1096023ec3da/small/15238.jpg)
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
![A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis](/images/research/a31e9e48-d1a1-4606-8b9c-3b33e87b570c/small/19845.jpg)
research A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
![Eph Receptors and Ephrins: Therapeutic Opportunities](/images/research/3d151b85-4d6c-4750-971d-d708a7dd6e73/small/14233.jpg)
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.