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300-330 / 1000+ resultsresearch Induced Pluripotent Stem Cell Approach to Hair Follicle Regeneration
![Emerging interactions between skin stem cells and their niches](/images/research/2a658f0a-a4dc-4976-8fa0-1cf4880d90b7/small/12822.jpg)
research Emerging interactions between skin stem cells and their niches
Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
![Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis](/images/research/ffec4c6e-3d28-41d9-bb2c-f228ce6325fb/small/12645.jpg)
research Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis
Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
research Wound Healing Induced Hair Follicle Regeneration
![Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration](/images/research/048a4ce6-d3e9-4b2a-9c2b-6eaa0d9f68a1/small/12624.jpg)
research Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration
Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.
research Bioengineered polyester nanoparticles for the synergistic treatment of androgenic alopecia via the suppression of 5α-reductase and knockdown of androgen receptor
![Dermal papilla cells induce keratinocyte tubulogenesis in culture](/images/research/702c4f3c-d292-444a-89c9-fb5e3f368041/small/30924.jpg)
research Dermal papilla cells induce keratinocyte tubulogenesis in culture
Skin cells can help create early hair-like structures in lab cultures.
![Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold](/images/research/e82e5e97-0a7f-4c93-a079-ec1d0e9e692d/small/34206.jpg)
research Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold
The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
![Human basal cell carcinoma: the induction of anagen hair follicle differentiation](/images/research/9b59be6a-0ec1-4fa9-ba45-d116fc9e1561/small/34130.jpg)
research Human basal cell carcinoma: the induction of anagen hair follicle differentiation
Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.
![Editorial: Hair Follicle Stem Cell Regeneration in Aging](/images/research/414e2a55-66eb-4171-98ce-1b9d72d43591/small/17076.jpg)
research Editorial: Hair Follicle Stem Cell Regeneration in Aging
Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
![ILK modulates epithelial polarity and matrix formation in hair follicles](/images/research/665a7692-21ca-42a5-94a6-f347b2feb9fd/small/36514.jpg)
research ILK modulates epithelial polarity and matrix formation in hair follicles
ILK is essential for proper hair follicle development and structure.
![Isolation of adipose-derived stem cells by using a subfractionation culturing method](/images/research/73d28b69-629f-454a-b9e2-7808cdd91a52/small/23094.jpg)
research Isolation of adipose-derived stem cells by using a subfractionation culturing method
The new method for isolating stem cells from fat is simple and effective, producing cells that grow faster and are better for hair regeneration.
![1390 Active hair growth is fuelled by conveyor-belt like differentiation of germinative layer cells](/images/research/85ebc4a3-700c-4355-b5db-13a7a92559ff/small/19100.jpg)
research 1390 Active hair growth is fuelled by conveyor-belt like differentiation of germinative layer cells
Hair growth is driven by cells that move and change like a conveyor belt.
![Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline](/images/research/4b137684-f7d3-46e9-8507-20a099b84486/small/19034.jpg)
research Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline
More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
![Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation](/images/research/4368cc84-cdb2-4927-a426-2d7df4bb30d0/small/29041.jpg)
research Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
![Dermal papilla regulation of hair growth and pigmentation](/images/research/34ff9d11-2b8f-45a9-805b-5bb7ce68f6aa/small/17776.jpg)
research Dermal papilla regulation of hair growth and pigmentation
Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
![Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo](/images/research/92c8944e-1bf3-4cf1-996d-5b8eccfc6e11/small/19839.jpg)
research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo
Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
![Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells](/images/research/87091211-b86c-46fe-a98d-8ee94db1885d/small/12859.jpg)
research Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells
Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.
![β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair](/images/research/f22ee802-ae0e-43cf-84ca-3528bdd5f498/small/19905.jpg)
research β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair
β-catenin in the dermal papilla is crucial for normal hair growth and repair.
![Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells](/images/research/a485ce31-318c-422e-ab8f-02cafe9583be/small/18295.jpg)
research Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells
Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
![A review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration](/images/research/bf9a7368-d1aa-4e38-b5bb-d7fb27445fc7/small/3496.jpg)
research A review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration
Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
![Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach](/images/research/89fa837c-85fb-4ca8-a9e9-f3de1106a9a5/small/14474.jpg)
research Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach
The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.
![Methods for the isolation and 3D culture of dermal papilla cells from human hair follicles](/images/research/61e50430-3ea1-4227-979b-68f6ed86cd8d/small/18212.jpg)
research Methods for the isolation and 3D culture of dermal papilla cells from human hair follicles
The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
![Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia](/images/research/bab71667-5bae-485f-b9a6-ee505db21381/small/3972.jpg)
research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
![TGF‐β<sub>2</sub> is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis](/images/research/7886a053-45d8-414f-9112-1031027daae3/small/30923.jpg)
research TGF‐β2 is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
![Induction of hair follicle neogenesis with cultured mouse dermal papilla cells in de novo regenerated skin tissues](/images/research/e24e385d-683e-422f-98fa-852ea2ee3285/small/11461.jpg)
research Induction of hair follicle neogenesis with cultured mouse dermal papilla cells in de novo regenerated skin tissues
Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
![miR-195-5p Regulates Hair Follicle Inductivity of Dermal Papilla Cells by Suppressing Wnt/<i>β</i>-Catenin Activation](/images/research/c9f03037-13b8-412d-ab14-f6f63ca36467/small/26297.jpg)
research miR-195-5p Regulates Hair Follicle Inductivity of Dermal Papilla Cells by Suppressing Wnt/β-Catenin Activation
miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.
![TGFβ family mimetic peptide promotes proliferation of human hair follicle dermal papilla cells and hair growth in C57BL/6 mice](/images/research/bd470350-aa54-45b0-9b91-aa8e4e0a1478/small/22968.jpg)
research TGFβ family mimetic peptide promotes proliferation of human hair follicle dermal papilla cells and hair growth in C57BL/6 mice
A peptide called DPS-1 helps human scalp cells grow and stimulates hair growth in mice.
![Detecting the Mechanism behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus nippon) Dermal Papilla Cells to Three-Dimensional Pattern](/images/research/1360d02f-d484-4b8e-afea-474b86271840/small/17227.jpg)
research Detecting the Mechanism behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus nippon) Dermal Papilla Cells to Three-Dimensional Pattern
The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.