Active Hair Growth Is Fuelled by Conveyor-Belt Like Differentiation of Germinative Layer Cells

April 2023 in “ Journal of Investigative Dermatology ”

K. Annusver, D. Pereira, D. Fernandex … I. Sequeira

hair growth germinative layer cells single-cell RNA-sequencing single-molecule mRNA FISH in vivo lineage-tracing matrix progenitor cells dermal papilla medulla niche Lgr5 Dcn Id3 Msx1 Lef1 inner hair follicle layer

Studysummary This study found that matrix progenitor cells in hair follicles move in a conveyor-belt-like fashion along the dermal papilla, changing their transcriptional states and lineage potential as they differentiate into inner hair follicle layers.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

Read the full study on jidonline.org →

Discuss this study in the Community →

Related research 7

Possible Cellular Communication with Human Follicle Dermal Papilla Cells via Secretions from Human Hair Follicle Keratinocytes Journal of St. Marianna University · 2022
A Model System to Analyze the Ability of Human Keratinocytes to Form Hair Follicles Experimental Dermatology · 2014
Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
Hair Follicle Reformation Induced by Dermal Papilla Cells from Human Scalp Skin Archives of Dermatological Research · 2006
Study on Hair Follicle Formation Induced by Dermal Papilla Cells Chinese Journal of Reparative and Reconstructive Surgery · 2003
Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001
Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles Wound Repair and Regeneration · 1998