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    Glossary OVOL1

    gene regulating hair follicle cell differentiation and hair cycle

    OVOL1 is a gene that plays a crucial role in the regulation of hair growth and development. It encodes a transcription factor that helps control the differentiation of hair follicle cells, influencing the transition from the growth phase (anagen) to the resting phase (telogen) of the hair cycle. Mutations or dysregulation of OVOL1 can be associated with hair disorders, including certain types of alopecia.

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    Research 30 of 82

    1. Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and in Pilomatricoma American Journal of Pathology · 2016 · 20 citations
    2. Activation of the OVOL1-OVOL2 axis in the hair bulb and in pilomatricoma and pilomatrix carcinoma Journal of dermatological science · 2016
    3. LB999 Role of transcription factor Ovol2 in skin epithelial regeneration and repair Journal of Investigative Dermatology · 2017
    4. An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation EMBO Reports · 2018 · 30 citations
    5. 1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia Journal of Investigative Dermatology · 2018
    6. Twist1 is required for the development of UVB‐induced squamous cell carcinoma Molecular Carcinogenesis · 2021 · 11 citations
    7. OVO Homolog-Like 1, a Target Gene of the Wnt/β-Catenin Pathway, Controls Hair Follicle Neogenesis Journal of Investigative Dermatology · 2013 · 9 citations
    8. Follistatin and secreted frizzled-related protein 1, OVO homolog-like 1-regulated genes, are important for hair follicle neogenesis Experimental Dermatology · 2015 · 4 citations
    9. Transcriptional Control of Epidermal Stem Cells Advances in Experimental Medicine and Biology · 2013 · 4 citations
    10. 854 CCL5 affects the hair-inductive capacity of three-dimensional (3D)-cultured dermal papilla cells Journal of Investigative Dermatology · 2017 · 1 citations
    11. Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration 2019
    12. 1397 LSD1 is critical for epidermal development and skin barrier formation Journal of Investigative Dermatology · 2023
    13. 1459 WITHDRAWN Journal of Investigative Dermatology · 2018
    14. The role of Twist1 in UVB-induced skin carcinogenesis 2020
    15. Evaluation of Gene Expression Patterns in Micrografts Demonstrate Induction of Catagen-Like Processes During Storage Dermatologic Surgery · 2017 · 5 citations
    16. 859 Building a functional niche for hair follicle stem cells Journal of Investigative Dermatology · 2017
    17. From basic biology to engineered therapies: the keratinocyte stem cell playbook Frontiers in Medical Technology · 2026
    18. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005 · 417 citations
    19. Aging in hair follicle stem cells and niche microenvironment The Journal of Dermatology · 2017 · 38 citations
    20. Genome-wide meta-analysis identifies novel loci conferring risk of acne vulgaris European Journal of Human Genetics · 2023 · 29 citations
    21. What does acne genetics teach us about disease pathogenesis? British Journal of Dermatology · 2019 · 29 citations
    22. The relationship among androgens, insulin resistanceand ghrelin polymorphisms in post-adolescent malepatients with severe acne vulgaris Advances in Dermatology and Allergology · 2020 · 10 citations
    23. Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 2 citations
    24. Single-cell chromatin landscapes of mouse skin development Scientific Data · 2022 · 2 citations
    25. Upadacitinib in dermatologic therapy: Emerging evidence and expanding indications Journal of Skin and Sexually Transmitted Diseases · 2026
    26. Aged differentiated cells reverse into native stemness-like state by niche cytokines to sustain lifelong homeostasis and tissue repair Nature Communications · 2026
    27. Investigating tralokinumab-related adverse events in treating atopic dermatitis: insights from the FAERS database Frontiers in Immunology · 2026
    28. More than one way to skin . . . Genes & Development · 2008 · 218 citations
    29. Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Clinical, Cosmetic and Investigational Dermatology · 2015 · 138 citations
    30. Role of vitamin D and calcium signaling in epidermal wound healing Journal of endocrinological investigation · 2022 · 15 citations