Topical Application of Newly Developed Pseudoceramide Improved Both Skin and Hair Barrier Functions

The document reports on a study that investigated the effects of a newly developed pseudoceramide, bis-oleamido isopropyl alcohol (BOIP), on skin and hair barrier functions. The study found that topical application of BOIP led to accelerated recovery of epidermal permeability barrier function in an acute disruption model and increased expression of anti-microbial peptides in cultured human epidermal keratinocytes. Additionally, biomechanical analysis revealed that applying Ceramide HS to damaged hair improved its mechanical strength and surface friction. These findings suggest that BOIP has beneficial effects on both skin and hair, indicating its potential use in scalp care products. However, the document does not provide specific details on the number of subjects or the experimental design, which are important for assessing the strength of the study.