December 2024 in “Journal of Pakistan Association of Dermatologists” This article reviews the causes, diagnosis, and treatment options for hirsutism in females, noting its connection to conditions like PCOS and highlighting the emotional distress it can cause.
14 citations
,
August 1997 in “The Journal of Urology” Finasteride can cause enlarged breasts.
January 2024 in “Medicina” This study assessed outcomes and complications of upper-face feminization surgery among 20 transgender patients, highlighting that insufficient browbone reduction was a common issue in prior surgeries, and emphasizing meticulous planning to prevent revisions and dissatisfaction.
1 citations
,
July 2022 in “BMC Women s Health” This report describes a rare case of elevated serum DHEAS levels in a postmenopausal woman, linked to an ovarian sex cord-stromal tumor rather than the adrenal glands, challenging common assumptions about androgen sources.
18 citations
,
January 2023 in “Nano Research” This study found that red OLED irradiation can significantly promote hair regrowth in mice, increasing hair length by 1.5 times and hair regrowth area by over 3 times after 20 days of treatment.
4 citations
,
August 2025 in “Journal of Ovarian Research” This study focused on categorizing the research status of natural products for improving ovary and uterus quality, fertility, and weight loss in PCOS, but noted a lack of continuous studies connecting basic research to clinical trials.
March 2026 in “IntechOpen eBooks” This chapter explores the promising use of low-power laser irradiation for post-hysterectomy reconstructive care, emphasizing enhancements like a flexible fiber optic module, to potentially improve genitourinary rehabilitation in cervical cancer patients.
77 citations
,
September 1983 in “Acta Paediatrica” In this study, administering dexamethasone rapidly normalized elevated steroid levels in girls with premature adrenarche.
4 citations
,
January 1991 in “Journal of dermatological treatment” This study found that GnRH-A treatment significantly reduced hirsuties scores in women with mild idiopathic hirsuties but did not affect hair growth rate or diameter.
9 citations
,
January 2023 in “Cellular and Molecular Life Sciences” This study found that intrauterine administration of botulinum toxin A improved endometrial environment and receptivity in a murine model of thin endometrium through mechanisms involving IGFBP3 and osteopontin.
August 2024 in “Archives of Women s Mental Health” This study found that women with PCOS exhibited higher levels of depression, tension induction, and impaired stress coping strategies compared to healthy controls, with these psychological issues correlating with hyperandrogenism but not with central obesity or insulin resistance.
35 citations
,
January 2005 in “Brain Research” This study indicates that progesterone’s anesthetic activity in PR knockout mice is not due to progesterone receptors but is partially mediated by the neurosteroid allopregnanolone through GABAA receptor potentiation.
2 citations
,
November 2019 in “Journal für Klinische Endokrinologie und Stoffwechsel” This review discusses the complex and variable presentation of polycystic ovary syndrome, emphasizing the need for consistent diagnostic criteria and individualized treatment strategies but reports no new clinical results.
5 citations
,
October 2014 in “Gynecological Endocrinology” This case study describes a 15-year-old girl with a Sertoli–Leydig cell tumor who showed high androgen levels and steroidogenic responses similar to patients with polycystic ovary syndrome before surgery.
In this case report, a 54-year-old woman with hirsutism was found to have a benign ovarian cystadenofibroma, which resolved after surgery, highlighting the importance of evaluating postmenopausal women for ovarian causes of androgen excess.
1 citations
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January 2021 in “Prague medical report” This article reviews the potential male equivalent of polycystic ovarian syndrome, focusing on hormonal alterations and premature androgenic alopecia, but reports no new clinical findings; the authors highlight the need for further studies on adrenal steroids and other factors.
July 2025 in “Annals of Medicine” This study describes a planned multicenter randomized controlled trial to assess the safety, tolerability, and pharmacokinetics of subdermal gestrinone pellets in patients with deep infiltrative endometriosis-related pelvic pain, but it does not report any findings yet.
1 citations
,
January 2023 This article reviews the causes and treatment options for hyperandrogenism-related hirsutism and acne in women, reporting no new results and highlighting the variability in treatment needs based on severity and personal desire.
9 citations
,
March 2022 in “Journal of the Endocrine Society” This study found that testosterone more accurately predicts PCOS diagnosis than 11-oxyandrogens, which were linked with hirsutism severity and showed varying responses to contraceptive and metformin treatments.
7 citations
,
January 2011 in “Journal of The American Academy of Dermatology” This study observed that moderate to severe acne is the most common manifestation in women with hyperandrogenism and highlights acanthosis nigricans and hirsutism as useful clinical markers.
5 citations
,
July 1987 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study found that a combined oral contraceptive containing ethinyl estradiol and desogestrel appeared effective in temporarily treating ovarian hyperandrogenism in adolescents, with reductions in hormone levels and ovarian volume observed.
June 2022 in “Journal of Education, Health and Sport” This article reviews current acne treatments linked to polycystic ovary syndrome in adults but reports no new clinical findings.
August 2022 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that the prevalence of PCOS among adolescent and young girls in India was 7.21%, with dysmenorrhea and acne being common symptoms.
2 citations
,
August 2022 in “Reproductive Biology and Endocrinology” This study found that magnesium supplementation significantly improved overall quality of life in women with polycystic ovary syndrome, but did not significantly affect acne, alopecia, or abnormal uterine bleeding.
1 citations
,
October 2024 in “The Egyptian Journal of Hospital Medicine” This study found that androgenetic alopecia is the most prevalent form of hair loss among women with polycystic ovary syndrome in the Delta area of Egypt.
January 2024 in “Journal of Health Study and Medicine” This review discusses the types, preparation, and current applications of platelet-rich plasma in medicine, particularly focusing on its use in gynecology and obstetrics, but presents no new clinical results.
883 citations
,
August 2016 in “Nature Reviews Disease Primers” This review discusses the current understanding of polycystic ovary syndrome, focusing on its epidemiology, pathophysiology, diagnosis, management, and future research directions, but reports no new clinical results.
6 citations
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April 2009 in “Fertility and Sterility” Finasteride helps induce ovulation in nonresponder PCOS women.
1 citations
,
September 2023 in “Prostate International” In this study, a 12-week treatment with Angelicae Gigantis Radix and Glycyrrhizae Radix complex was well tolerated and showed therapeutic effects on moderate lower urinary tract symptoms in men.
67 citations
,
April 1988 in “The Journal of Clinical Endocrinology & Metabolism” This study describes a family with X-linked gynecomastia and undervirilization in men, finding a subtle androgen receptor abnormality that may not always lead to infertility despite androgen resistance.