Red Organic Light-Emitting Diodes Based Photobiomodulation Therapy Enabling Prominent Hair Growth

January 2023 in “ Nano Research ”

Shuang‐Qiao Sun, Jingjing Shen, Yufei Wang, Yutong Jiang, Lin-Fu Chen, Xin Hua, Jiangnan Wang, Xiaobo Shi, Xiao‐Zhao Zhu, Qi Sun, Liang‐Sheng Liao, Qian Chen, Man‐Keung Fung, Shuit‐Tong Lee

red organic light-emitting diodes photobiomodulation therapy alopecia hair follicle regeneration anagen phase autophagy microvascular blood flow OLEDs PBMT

Studysummary This study found that red OLED irradiation can significantly promote hair regrowth in mice, increasing hair length by 1.5 times and hair regrowth area by over 3 times after 20 days of treatment.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The study introduces red organic light-emitting diodes (OLEDs) as a novel photobiomodulation therapy (PBMT) for promoting hair growth, particularly in cases of alopecia. OLEDs offer advantages such as uniform light distribution, flexibility, and minimal heat production, making them suitable for wearable PBMT devices. The research demonstrates that OLEDs significantly enhance hair regrowth, increasing hair length by 1.5 times and expanding the regrowth area by over 3 times after 20 days of treatment. The study identifies two mechanisms by which OLEDs stimulate hair follicle regeneration: increased autophagy during the anagen phase and enhanced blood oxygen content due to improved microvascular blood flow, as evidenced by in-vivo experiments on mice.

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