87 citations,
March 2014 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
47 citations,
December 2011 in “Experimental Dermatology” CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.
4 citations,
September 2015 in “JAAD case reports” Substance P may play a role in the inflammation seen in keratosis follicularis spinulosa decalvans.
216 citations,
October 1997 in “American Journal of Ophthalmology” Using the eye pressure medication latanoprost can cause excessive hair growth and darker eyelashes on the treated eye.
8 citations,
July 2018 in “European Journal of Dermatology” A medication may help with hair growth in psoriasis, and a skin condition might be linked to a specific bacteria.
Oral Minoxidil can cause serious eye problems, but stopping it can improve vision.
5 citations,
July 1991 in “Irish Journal of Medical Science (1971 -)” Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.
44 citations,
July 2013 in “Journal of the American Academy of Dermatology” Poliosis circumscripta is a patch of white hair caused by lack of melanin, linked to genetic and acquired conditions.
April 2018 in “Journal of Investigative Dermatology” Hair pattern in androgenetic alopecia overlaps with scalp and bone demarcations, with distinct gene profiles affecting susceptibility.
8 citations,
August 2016 in “Acta dermato-venereologica” Timolol eye-drops can cause hair loss.
6 citations,
April 2022 in “Biomedicine & pharmacotherapy” Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
April 2018 in “Journal of Investigative Dermatology” The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.
55 citations,
September 2017 in “Journal of Cosmetic Dermatology” Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.
April 2018 in “Journal of Investigative Dermatology” A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.
April 2018 in “Journal of Investigative Dermatology” Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
November 2012 in “Endocrine Practice” Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
44 citations,
July 2012 in “Endocrine Practice” We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
182 citations,
October 2003 in “British Journal of Dermatology” The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.
24 citations,
November 2015 in “Frontiers in Genetics” Nitroxide drugs can safely and effectively treat age-related diseases like macular degeneration and cardiovascular issues.
May 2018 in “Journal of Investigative Dermatology” Fat under the skin can help hair grow longer, darker, and increase cell growth.
Newer retinoid drugs are effective for skin conditions but have significant side effects.
51 citations,
December 2017 in “Skin Appendage Disorders” Stress may trigger hair loss by affecting immune protection in hair follicles.
April 2018 in “Journal of Investigative Dermatology” Different types of stem cells in the skin contribute to the variety of melanoma forms.
59 citations,
June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
March 2024 in “Stem cell research & therapy” Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.
1 citations,
November 1976 in “Archives of Dermatology” Dermatopathology has made significant progress but many skin diseases remain incurable, requiring ongoing research.
7 citations,
April 2017 in “Dermatologic surgery” Hyaluronic acid fillers and combination treatments significantly improve facial defects from autoimmune diseases and are well-tolerated.
4 citations,
October 2013 in “Springer eBooks” Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
20 citations,
August 2019 in “Frontiers in immunology” Biologics show promise in treating various stubborn skin diseases, but more research and better reimbursement criteria are needed.
63 citations,
December 1988 in “International Journal of Dermatology” Vitiligo causes white skin patches and is linked to autoimmune issues.