Vitiligo

    December 1988 in “ International Journal of Dermatology ”
    R V Koranne, D. Derm., Karan Sachdeva
    Image of study
    TLDR Vitiligo causes white skin patches and is linked to autoimmune issues.
    Vitiligo, affecting at least 1% of the global population, was a significant sociopsychological issue, particularly in darker-skinned individuals. The exact cause was unclear, but hypotheses included genetic, autoimmune, neurogenic, and melanocyte self-destruction theories, with the autoimmune hypothesis supported by associations with other autoimmune conditions. Vitiligo presented as milky-white macules, often around body orifices and trauma areas, with an unpredictable course and usually insufficient spontaneous repigmentation. Histopathologically, it was marked by the absence of melanin and a mononuclear cell infiltrate at lesion margins. The disease was classified into three types based on melanocyte activity: absolute, relative type I, and relative type II. In 7 out of 50 cases, infiltrates caused basal cell layer dissolution, and inactive melanocytes could become active in repigmented areas.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 9 results

      community Fighting Hair loss AND Grey Hair

      in Treatment  19 upvotes 3 years ago
      The user is treating hair loss with topical Minoxidil, Finasteride, RU58841, microneedling, and Ketoconazole. For grey hair, they use L-Cysteine, L-Methionine, and PABA, and have noticed some re-pigmentation.

      community 1 Month Topical Minoxidil Only

      in Progress Pictures  72 upvotes 2 years ago
      The conclusion of the conversation is that the user plans to use topical minoxidil, ketoconazole shampoo, and a derma stamp for hair loss treatment. They also plan to start using finasteride in the next 2 months. Other users suggest using finasteride and a hair transplant for better results. The user appreciates the feedback and will continue posting progress.

      community 25M Exploring Causes of Hair Loss: TE, Alopecia, or AGA?

      in General  226 upvotes 1 week ago
      The user is experiencing hair loss with possible causes including chronic telogen effluvium, diffuse alopecia areata, and androgenic alopecia. They have tried treatments like Nizoral shampoo, minoxidil, and finasteride, and are considering a biopsy for further clarity.

      community One full year of treatment before and after

      in Progress Pictures  19 upvotes 1 year ago
      A user shared their one-year progress with hair loss treatment, using topical minoxidil, 2% keto shampoo, microneedling, and finasteride. They plan to start dutasteride and are considering switching to oral minoxidil.

    Similar Research

    5 / 1000+ results