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research Alopecia areata and risk of atopic and autoimmune conditions: population-based cohort study

34 citations , November 2022 in “Clinical and Experimental Dermatology”

This study found that individuals with AA have a higher incidence of atopic and autoimmune conditions, suggesting both Th1 and Th2 immune responses may play a role in its development.

Epidemiology, Management, and the Associated Burden of Mental Health Illness, Atopic and Autoimmune Conditions, and Common Infections in Alopecia Areata: Protocol for an Observational Study Series

research Epidemiology, management and the associated burden of mental health illness, atopic and autoimmune conditions, and common infections in alopecia areata: protocol for an observational study series

11 citations , November 2021 in “BMJ Open”

This study reviews the epidemiology of alopecia areata in the UK, focusing on its links to mental health comorbidities, autoimmune/atopic associations, and common infection incidences.

research Characterization of an autoimmune condition associated with AEC syndrome

March 2016

This study found that genetic ablation of Tslp in an AEC mutant mouse model reduced skin inflammation and improved survival, suggesting potential therapeutic benefits for AEC syndrome patients.

research Alopecia areata: A multifactorial autoimmune condition

148 citations , December 2018 in “Journal of autoimmunity”

This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.

Prevalence of Autoimmune and Inflammatory Diseases and Mental Health Conditions Among an Alopecia Areata Cohort from a US Administrative Claims Database

research Prevalence of autoimmune and inflammatory diseases and mental health conditions among an alopecia areata cohort from a US administrative claims database

1 citations , June 2023 in “Journal of Dermatology”

This study found that patients with alopecia areata had a higher prevalence of autoimmune, inflammatory, and mental health conditions compared to a matched cohort without alopecia areata.

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Community Join

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community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Dutasteride thins eyebrows and facial hair but doesn't stop scalp loss.

in Finasteride/Dutasteride 37 upvotes 1 year ago

Dutasteride may not effectively stop scalp hair loss and can cause thinning of facial and body hair, including eyebrows. Users suggest considering other causes like autoimmune conditions or vitamin deficiencies and exploring treatments like finasteride or minoxidil.

community What is this pigmentation around my follicles?

in Chat 29 upvotes 1 year ago

The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

community fin 0.5 mg everday 6 months update

in Finasteride/Dutasteride 28 upvotes 2 years ago

The post discusses the experiences of individuals with diffuse hair thinning using finasteride, with many reporting no improvement or worsening conditions after 6 months. Various suggestions include persisting with the treatment, checking for underlying conditions, adding minoxidil for volume, adjusting dosage, and considering other potential causes like autoimmune responses and inflammation.

community My 15+ Year Hair Loss Journey: DUPA, Recurrent Alopecia Areata, & different dosages of Min / Fin topicals - Advice needed on next steps.

4 upvotes 1 week ago

The user has been managing hair loss for over 15 years, using treatments like Minoxidil, Finasteride, and corticosteroids, while experiencing side effects and recurrent Alopecia Areata. They seek advice on progression and potential underlying conditions, questioning if their hair loss is due to an autoimmune issue beyond typical patterns.

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Learn

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learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

What are the key limitations and considerations surrounding tofacitinib in hair loss products and therapies? Reported hair regrowth with tofacitinib comes from alopecia areata, an autoimmune condition — mostly from small, non-randomized studies, with relapse common after stopping. There is no good evidence it helps pattern hair loss, and it is not approved for hair loss anywhere.
What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and salicylic acid does not promote hair regrowth.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

learn Cetirizine

Could cetirizine help control autoimmune triggers in alopecia areata? No published trial has tested cetirizine in alopecia areata; one registered trial has not reported results. Small trials in pattern hair loss report modest benefit, so any use for alopecia areata is off-label and unproven.

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