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    GlossaryAutoimmune Diseases (Autoimmune Conditions)

    immune system attacks the body's own tissues

    Autoimmune diseases are conditions where the immune system mistakenly attacks the body's own tissues, thinking they are foreign invaders. This can lead to a variety of health issues, depending on which part of the body is targeted. Examples include rheumatoid arthritis, where joints are affected, and alopecia areata, where hair follicles are attacked, leading to hair loss.

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      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions
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      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

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      community What is this pigmentation around my follicles?

      in Chat  29 upvotes 2 weeks ago
      The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

      community Minoxidil can prevent hair follicle miniaturization!?

      in Minoxidil  6 upvotes 3 years ago
      Minoxidil can prevent hair follicle miniaturization, not just stimulate hair growth. Finasteride and dutasteride don't work for everyone, suggesting DHT may not be the sole cause of hair loss; hair loss could be due to multiple factors, including autoimmune conditions.

      community Treating my DUPA via controlling inflammation

      in Treatment  6 upvotes 11 months ago
      The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.
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      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 4 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  828 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.