Poliosis Circumscripta: Overview And Underlying Causes

July 2013 in “ Journal of the American Academy of Dermatology ”

Rima Sleiman, Mazen Kurban, Farah Succaria, Ossama Abbas

poliosis circumscripta melanin melanocytes hair follicles piebaldism Waardenburg syndrome tuberous sclerosis inflammatory diseases melanocytic neoplasms medication effects white hair genetic syndromes inflammatory conditions medication side effects

Studysummary This review discusses various genetic and acquired conditions associated with poliosis circumscripta and reports no new clinical results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Poliosis circumscripta, marked by localized white hair patches due to reduced or absent melanin or melanocytes in hair follicles, could occur on any hairy body area. It was linked to genetic syndromes such as piebaldism, Waardenburg, and tuberous sclerosis, as well as acquired conditions like inflammatory diseases, neoplastic entities, and medication effects. The review aimed to assist clinicians in evaluating patients with poliosis by detailing the various conditions associated with it.

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