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GlossaryPiebaldism

genetic condition causing white patches of skin and hair

Piebaldism is a rare genetic condition characterized by the absence of melanocytes, the cells responsible for producing pigment in the skin and hair. This results in patches of unpigmented (white) skin and hair, often noticeable from birth, and is typically inherited in an autosomal dominant pattern.

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research Piebaldism in Tree Shrews

September 1973 in “Primates”

research The Editor's Choice: Summary of Studies on Skin and Hair Conditions

June 2018 in “Journal of Dermatological Science”

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

research Long-Term Follow-Up of Leucoderma Patients Treated with Transplants of Autologous Cultured Melanocytes, Ultrathin Epidermal Sheets, and Basal Cell Layer Suspension

177 citations, November 2002 in “British journal of dermatology/British journal of dermatology, Supplement”

Transplantation is effective for stable leucoderma but not for progressive, widespread vitiligo vulgaris.

research Repigmentation of Leukoderma by Minigrafts of Normally Pigmented, Autologous Skin

56 citations, December 1978 in “The Journal of Dermatologic Surgery and Oncology”

Transplanting small skin grafts can successfully repigment leukoderma.

research Poliosis Circumscripta: Overview And Underlying Causes

44 citations, July 2013 in “Journal of the American Academy of Dermatology”

Poliosis circumscripta is a patch of white hair caused by lack of melanin, linked to genetic and acquired conditions.

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