Search

everythinglearnresearchcommunity

for

Search:↓

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

Fractional photothermolysis helps wounds heal with minimal scarring.

BRG1 is essential for skin cells to move and heal wounds properly.

Lamins are vital for cell survival, organ development, and preventing premature aging.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Histone modification is key in treating chronic inflammatory skin diseases.

Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.

Enzymes called PADIs play a key role in hair growth and loss.

Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Epigenetic mechanisms control skin development by regulating gene expression.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Maize hybrids show better early growth due to complex gene interactions from their parent strains.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Thiopurines help treat IBD but require genetic testing to avoid side effects.

Epigenetic factors play a crucial role in skin health and disease.

Late onset SLE has different symptoms and antibody profiles compared to young onset SLE.

A woman with lupus had rare severe symptoms but improved with treatment.

BAF200 is essential for proper heart and coronary artery formation.