Thiopurines: Recent Topics and Their Role in the Treatment of Inflammatory Bowel Diseases

    January 2021 in “ Frontiers in Pharmacology ”
    Keiichi Tominaga, Takeshi Sugaya, Takanao Tanaka … Atsushi Irisawa
    Studysummary This review examines the role of thiopurines in managing inflammatory bowel diseases like ulcerative colitis and Crohn's disease, and reports no new clinical results, emphasizing the need for more studies on thiopurine withdrawal scenarios.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 2

    1. NUDT15 R139C-Related Thiopurine Leukocytopenia Is Mediated by 6-Thioguanine Nucleotide-Independent Mechanism in Japanese Patients with Inflammatory Bowel Disease Journal of Gastroenterology · 2015
    2. Methotrexate for Maintenance of Remission in Ulcerative Colitis Cochrane library · 2015