TLDR Researchers found genes that may explain why some pigs grow winter hair, which could help breed cold-resistant pigs.
This study conducted a genome-wide association study (GWAS) on 573 Large White × Min F2 pigs to investigate the genetic basis of villi hair traits in Min pigs. Researchers identified 15 significant copy number variation regions (CNVRs) associated with these traits, with the most significant CNVR located on chromosome 1 near genes such as ASCC3, MCHR2, and SIM1. Functional enrichment analysis indicated these CNVRs are involved in biological processes like G-protein-coupled receptor signaling. The findings provide insights into the genetic mechanisms of cold resistance and could aid in breeding cold-resistant pigs. Further research is needed to confirm the functions of these genes in hair development.
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