This study found that in female androgenetic alopecia, androgen receptors are highly positive in affected areas, supporting their role as regulators of genetically predisposed hair follicles despite normal serum hormone levels.
3 citations
,
June 2020 in “Developmental Cell” This study observed that in chicken skin, large-scale differences in gene expression between feathered and scaly skin are controlled by enhancer-driven uniform expression, while small-scale differences within individual feathers are associated with chromatin looping.
92 citations
,
January 2013 in “Dermatology” This study reports a high prevalence of comorbid autoimmune conditions, particularly thyroid disorders and psoriasis, among vitiligo patients in Boston teaching hospitals.
79 citations
,
June 1993 in “Molecular and Cellular Biology” This study found that as few as 90 base pairs of the K5 promoter directed keratinocyte-preferred expression in stratified epithelia, especially in epidermis, hair follicles, and tongue, showing cell type specificity.
63 citations
,
December 2007 in “Lupus” This study found that Arabs with systemic lupus erythematosus in Dubai exhibit clinical features similar to SLE patients in other Arab and Western countries, with notable high prevalence of positive anti-Ro antibodies.
60 citations
,
December 1988 in “Journal of Biochemical Toxicology” In this study, TCDD administered to male rats down-regulated EGF receptor in liver plasma membranes and increased protein kinase activity, suggesting EGF receptor–mediated toxicological effects.
22 citations
,
June 2013 in “Australasian Journal of Dermatology” Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.
12 citations
,
July 2015 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that mechanical damage from grooming and environmental factors contributes to crack formation and eventual breakage in African-American hair, highlighting the need for continuous care.
9 citations
,
January 2013 in “Indian journal of dermatology, venereology, and leprology” Infliximab may cause hair loss in Crohn's disease patients.
7 citations
,
March 2021 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” In this study, bromocriptine's inhibition of prolactin promoted secondary follicle development during anagen in cashmere goats, likely via changes in specific gene expressions, despite not affecting fiber characteristics or primary follicle activity.
7 citations
,
October 2017 in “Journal of exotic pet medicine” This case report documents a 3-year-old guinea pig with hormonally active ovarian cysts, cystic endometrial hyperplasia, and bacterial endometritis associated with a uterine foreign body.
4 citations
,
June 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This case report describes a 30-year-old woman diagnosed with both Rhupus and Rowell syndromes, and details her presentation and treatment plan, without reporting specific treatment outcomes.
3 citations
,
June 2020 in “Open access rheumatology” This case report reviews the management of Rowell syndrome in a patient initially diagnosed with Rhupus syndrome and highlights their development of erythema multiforme after certain medications.
1 citations
,
June 2023 in “Journal of applied crystallography” This study utilized the DNP–SANS technique on human hair for the first time and found significant changes in the SANS profile dependent on polarization conditions, providing insights into the structural composition and dynamic properties of keratin and its associated proteins.
1 citations
,
February 2023 in “International Journal of Rheumatic Diseases” This study reported that tuberculosis can mimic lupus-like symptoms, including the production of autoantibodies, which may confuse the diagnosis with systemic lupus erythematosus flares.
January 2026 in “Regenerative Biomaterials” This study synthesized and compared single-ion doped silicate bioactive glass nanoparticles for tissue repair, finding that BSr and BCe were most effective in accelerating wound healing and restoring vasculature, with BSr particularly reducing inflammation and BCo enhancing hair follicle regeneration but with limited biosafety window.
August 2023 in “The American Journal of Medicine” This case report describes a 17-year-old female patient diagnosed with systemic lupus erythematosus, presenting with arthralgia, hair loss, and Raynaud's phenomenon. The diagnosis was supported by elevated ESR and positive autoantibodies, and treatment included hydroxychloroquine and prednisone.
July 2023 in “Journal of Ayub Medical College Abbottabad” This case study details a 30-year-old woman diagnosed with Lupus Vasculitis, presenting with symptoms like intermittent fever, joint pain, and respiratory issues, after tests revealed specific antibody patterns and reduced complement levels, leading to treatment with steroids, mycophenolate mofetil, and hydroxychloroquine.
January 2023 in “Indian dermatology online journal” This case study describes a previously unknown association of the PIBIDS complex with autoimmune thyroiditis and autoimmune hemolytic anemia in a five-year-old Indian child.
August 2018 in “International Journal of Research in Dermatology” In this study, cutaneous features like hair loss, malar rash, and photosensitivity were identified as key indicators of disease activity in systemic lupus erythematosus.
April 2018 in “African journal of rheumatology” This case report describes a teenager with Systemic Lupus Erythematosus experiencing neuropsychiatric symptoms, highlighting diagnostic criteria and laboratory findings, but reports no new treatment outcomes.
This case report describes a 21-year-old man diagnosed with systemic lupus erythematosus, highlighting the condition's potential to mimic hematological malignancy and the effectiveness of prednisolone in rapid symptom improvement.
This study identified 92 novel regulators of melanogenesis, highlighting Aldehyde dehydrogenase 1A1 as a potential target for developing new treatments for hyperpigmentation disorders like melasma.
January 2014 in “Journal of Jilin University” This study found that Th22 cells and their cytokine IL-22 may play an important role in the pathogenesis of systemic lupus erythematosus and could serve as bioindicators for monitoring disease severity.
This study suggests that Arabs with systemic lupus erythematosus in Dubai show similar clinical features to patients from other Arab and Western countries, with a notable prevalence of positive anti-Ro antibodies.
September 2004 in “Experimental dermatology” This study found that normal murine hair follicles are direct targets for melatonin bioregulation, expressing receptors that are regulated in a hair cycle-dependent manner, influencing keratinocyte apoptosis.
170 citations
,
November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that in the absence of hair follicles, cutaneous wounds in mice showed delayed reepithelialization but eventually achieved normal wound closure after expanding the activated epidermis region.
113 citations
,
June 2015 in “Stem Cell Research & Therapy” This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.
56 citations
,
February 2013 in “International Journal of Molecular Medicine” This study found that human hair follicle-derived mesenchymal stem cells maintained their proliferation and differentiation potential when cultured with acidic fibroblast growth factor, basic fibroblast growth factor, or epidermal growth factor.
49 citations
,
February 2009 in “Clinical Rheumatology” This study observed that systemic lupus erythematosus may not be as uncommon among African Blacks as previously reported, highlighting the need for early aggressive treatment.