Cutaneous Manifestations and Systemic Correlation in Patients with Lupus Erythematosus and Its Subsets: A Study of 40 Cases
August 2018
in “
International Journal of Research in Dermatology
”
Studysummary In this study, cutaneous features like hair loss, malar rash, and photosensitivity were identified as key indicators of disease activity in systemic lupus erythematosus.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study examined 40 patients with lupus erythematosus (LE) and its subsets, finding that 97.5% had cutaneous involvement, including photosensitivity (77.5%), oral ulcers, hair loss, and malar rash. Systemic lupus erythematosus (SLE) was the most common subset (22 cases), followed by discoid lupus erythematosus (DLE) (13 cases), Rowell’s syndrome (4 cases), and mixed connective tissue disorder (MCTD) (1 case). Hematological involvement and positive anti-nuclear antibody (ANA) titers were prevalent in SLE and Rowell’s syndrome. The study concluded that cutaneous features, particularly hair loss, malar rash, and photosensitivity, are key indicators of disease activity in SLE.
