Cutaneous Manifestations and Systemic Correlation in Patients with Lupus Erythematosus and Its Subsets: A Study of 40 Cases

August 2018 in “ International Journal of Research in Dermatology ”

Rashmi Mahajan, Kishan Ninama, Ishan Pandya, Rajvee Patel, FE Bilimoria

hair loss photosensitivity malar rash systemic lupus erythematosus discoid lupus erythematosus Rowell’s syndrome mixed connective tissue disorder anti-nuclear antibody SLE DLE ANA

TLDR Skin issues like hair loss, rash, and sensitivity to sunlight are key signs of lupus activity.

The study examined 40 patients with lupus erythematosus (LE) and its subsets, finding that 97.5% had cutaneous involvement, including photosensitivity (77.5%), oral ulcers, hair loss, and malar rash. Systemic lupus erythematosus (SLE) was the most common subset (22 cases), followed by discoid lupus erythematosus (DLE) (13 cases), Rowell’s syndrome (4 cases), and mixed connective tissue disorder (MCTD) (1 case). Hematological involvement and positive anti-nuclear antibody (ANA) titers were prevalent in SLE and Rowell’s syndrome. The study concluded that cutaneous features, particularly hair loss, malar rash, and photosensitivity, are key indicators of disease activity in SLE.

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Research cited in this study

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research Cutaneous Lupus Erythematosus: A Review

149 citations, July 2002 in “Dermatologic clinics”

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

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community Scalp Sunburns can cause permanent hair loss. UPF hats protect you.

in Technology 3 months ago

Scalp sunburns can cause permanent hair loss, so wearing UPF hats is essential. Tretinoin and Tacrolimus users should be cautious of increased photosensitivity and potential scalp issues.

community Scalp Sunburns cause permanent hair loss. UPF hats protect you. Watch if you use Tretinoin on the scalp

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Sunburns on the scalp can cause permanent hair loss, especially for those using Tretinoin or Tacrolimus. Wearing UPF 50+ hats is recommended to protect against UV radiation.

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community Medications that cause extra hair growth

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The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community Obviously, all of us who are serious take antiandrogens and growth stimulants - what else are you doing lifestyle wise, dietary wise, and regiment wise to maximize your results?

in Treatment 21 upvotes 5 months ago

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research Immunological And Some Biological Biomarkers Investigation In Patients With Systemic Lupus Erythematosus

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No single biomarker is reliable enough for diagnosing and assessing SLE.