Alopecia Areata in a Patient Receiving Infliximab

January 2013 in “ Indian journal of dermatology, venereology, and leprology ”

N. Ormaechea‐Pérez, A. López-Pestaña, Ana Isabel Muñagorri-Santos, Ane Jaka, A. Tuneu-Valls

alopecia areata infliximab methotrexate anti-nuclear antibodies scalp biopsy non-scarring hair loss AA Remicade

TLDR Infliximab may cause hair loss in Crohn's disease patients.

A 36-year-old woman with Crohn's disease developed alopecia areata (AA) after 9 months of infliximab treatment. The AA manifested as non-scarring hair loss on the scalp, eyebrows, and eyelashes. Blood tests showed positive anti-nuclear antibodies, and a scalp biopsy confirmed AA. Discontinuing infliximab and starting methotrexate led to complete hair regrowth and normalization of antibody levels within 2 months. The case suggested that infliximab might trigger AA by altering immune pathways, and this was the first reported instance of AA in a Crohn's disease patient treated with infliximab.

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research Alopecia Areata in a Patient Receiving Infliximab

9 citations, January 2013 in “Indian journal of dermatology, venereology, and leprology”

Infliximab may cause hair loss in Crohn's disease patients.