Water Distribution in Human Hair Microstructure Elucidated by Spin Contrast Variation Small-Angle Neutron Scattering

    Yohei Noda, Satoshi Koizumi, Takeshi Maeda … Aya Ishihara
    Studysummary This study utilized the DNP–SANS technique on human hair for the first time and found significant changes in the SANS profile dependent on polarization conditions, providing insights into the structural composition and dynamic properties of keratin and its associated proteins.
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    Research cited in this study 9

    1. Structure of Intermediate Filament Assembly in Hair Deduced from Hydration Studies Using Small-Angle Neutron Scattering Journal of structural biology · 2019
    2. Local Structure of Human Hair Spatially Resolved by Sub-Micron X-Ray Beam Scientific reports · 2015
    3. A Novel Purification Procedure for Keratin-Associated Proteins and Keratin from Human Hair Journal of Biological Macromolecules · 2013
    4. Structural Analysis of Human Hair Single Fibers by Scanning Microbeam SAXS Journal of Structural Biology · 2006
    5. The Intermediate Filament Architecture as Determined by X-Ray Diffraction Modeling of Hard Alpha-Keratin Biophysical Journal · 2004
    6. Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain Journal of Investigative Dermatology · 2000
    7. Organization of Microfibrils in Keratin Fibers Studied by X-Ray Scattering Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 1998
    8. Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes Journal of biological chemistry/˜The œJournal of biological chemistry · 1998
    9. Structure and Biochemistry of Mammalian Hard Keratin Electron Microscopy Reviews · 1991