2 citations
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September 2024 in “Asian Journal of Pharmaceutics” This research discusses advancements in niosomal drug delivery systems, highlighting their promising potential to improve targeted drug delivery due to their ability to encapsulate various drug types efficiently, offering advantages over traditional liposome systems in terms of chemical stability and therapeutic efficacy.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that the Keyora Lycopene 23 in 1 formulation may improve various aspects of male endocrine and reproductive health by targeting oxidative stress, nitric oxide deficiency, and hormonal imbalance.
November 2025 in “Journal of English Language and Education” In this study, researchers found that a hair tonic formulated with 2% guava leaf extract demonstrated strong consumer acceptance and safe physicochemical characteristics among university students, showing potential as a natural alternative for reducing hair loss.
2 citations
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November 2019 in “Jurnal Penelitian Perawat Profesional” This literature review concludes that mulberry, with its rich anthocyanin, phenolic, and antioxidant content, may serve as an effective adjuvant therapy for preventing and managing obesity by reducing body fat levels.
July 2026 in “Journal of the American Academy of Dermatology” August 2025 in “Journal of Medical and Biological Engineering” In this study, a needle-free supersonic atomizer delivering Bacopa monnieri extract with hyaluronan was found to enhance hair growth in mice more effectively than the traditional smear method and minoxidil.
This study suggests that Yonnyuniksoogobon-dan promotes hair growth in C57BL/6 mice, potentially through up-regulating EGF and VEGF and down-regulating iNOS near hair roots.
June 2026 in “Current Issues in Molecular Biology” In this study, a botanical extract and minoxidil showed similar effects in vitro by reducing pro-inflammatory cytokines and 5α-reductase expression while increasing growth factors VEGF and KGF in human keratinocyte cells, suggesting potential for further in vivo research.
August 2024 in “Proceeding Cendekia International Conference Health and Technology” In this quasi-experimental study, researchers explored the optimal formulation of a nanoemulsion containing candlenut ethanol extract, finding that specific combinations of tween 80, span 80, and sonication time affected its physical properties and stability, although further activity testing is needed.
7 citations
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January 2025 in “Journal of Medicinal Chemistry” This study identified orally available itaconate derivatives that improve cellular permeability and bioavailability, with specific POC-based prodrugs showing significant inhibition of inflammatory cytokines in human epidermal keratinocytes and favorable oral pharmacokinetics, highlighting their potential for treating systemic and skin disorders.
1 citations
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January 2014 This study found that Crataegus pinnatifida extract promoted hair growth in mice by inducing the anagen phase, potentially through activating signaling pathways that enhance cell survival.
November 2023 in “Research Journal of Pharmaceutical Dosage Forms and Technology” This study observed that a herbal oil made from plant extracts including Embica officinalis and Bacopa monnieri significantly promoted hair growth, with different preparation methods yielding effective results.
2 citations
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May 2025 in “PLoS ONE” This study found that a 4:1 combination of Rhynchosia nulubilis and Polygonum multiflorum extracts significantly promoted the proliferation of human dermal papilla cells and alleviated testosterone-induced cytotoxicity, suggesting potential for treating hair loss and related disorders through a synergistic approach.
September 2025 in “Polymer Korea” In this study, a parsley-derived n-hexane fraction formulated into a coconut oil-based nanoemulsion demonstrated significant hair regrowth comparable to 3% minoxidil, with near-complete coverage by day 17, suggesting potential as a topical hair growth treatment.
45 citations
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March 2020 in “International Journal of Nanomedicine” This study found that nanoemulsion-based formulations, such as nanoemulgel and NFs, might serve as promising topical delivery systems for treating inflammatory diseases, potentially offering an alternative to traditional nonsteroidal anti-inflammatory drugs, which are associated with adverse effects.
36 citations
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October 2019 in “Cell Proliferation” This study reported that tryptanthrin, a compound found in indigo naturalis, effectively suppresses non-melanoma skin cancer in mice by reducing inflammation, inhibiting cell proliferation, and blocking specific signaling pathways associated with tumor growth.
May 2023 in “Journal of Pharmaceutical Research” This article reviews the extensive pharmacological applications of various parts of the neem plant, such as anticancer, anti-inflammatory, and antimicrobial effects, and reports no adverse effects except for allergic reactions, concluding neem is broadly beneficial with numerous medicinal and cosmetic uses.
36 citations
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March 2014 in “Biomaterials” This study found that the 11R-No. 10 peptide, delivered transdermally, significantly inhibited melanogenesis and produced a whitening effect in a UV-induced sun-tanning guinea pig model without cytotoxicity.
2 citations
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August 2019 in “Asian journal of pharmaceutical and clinical research” This study found that in female breast cancer patients, supplementation with 400 mg IND02 (Cinnamon bark extract) thrice daily during chemotherapy significantly reduced severe weight loss and hair loss compared to placebo, with the treatment being well-tolerated and safe.
January 2018 in “BiblioBoard Library Catalog (Open Research Library)” 14 citations
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February 2025 in “Pharmaceutics” This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.
1 citations
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July 2017 in “Global journal of pharmacy & pharmaceutical sciences” The study explored niosome formulations containing minoxidil and tretinoin and found increased drug stability and controlled release, suggesting potential as an effective drug delivery system for treating hair loss.
January 2024 in “Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)” In this review, the authors discuss the anti-cancer potential of luteolin, a plant-derived compound, highlighting its limitations in bioavailability and solubility, as well as exploring the enhanced efficacy of luteolin when formulated in nanoparticles for cancer treatment.
3 citations
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January 2023 in “Agronomy” This research reported that KDML105 bran extract demonstrated antioxidant activities, reduced nitric oxide production, and influenced gene expression related to the hair cycle in cultured dermal papilla cells, suggesting potential as an anti-hair loss agent by supporting the anagen phase and angiogenesis.
March 2024 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that minoxidil nanoparticles significantly increased hair growth in mice compared to commercial minoxidil and rosemary extract, demonstrating improved delivery and follicular uptake.
In a study on female Wistar rats, researchers found that a hair tonic containing a 7.5%:2% combination of talok and pare leaf extracts increased hair growth comparable to minoxidil, showing similar efficacy in promoting hair growth without significant statistical difference.
November 2023 in “PubMed” This study found that treating mice with naringenin, alone or combined with minoxidil, significantly increased hair growth and follicle diameter and quantity, likely due to its antioxidant and anti-inflammatory properties.
15 citations
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September 2006 in “Journal of International Medical Research” This study found that Nourkrin®, based on marine proteins, significantly improved hair growth in participants with hair loss, with good tolerability and no reported side effects.
9 citations
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January 2015 in “Laboratory Animal Research” This study found that oral administration of Laminaria japonica and Cistanche tubulosa extracts may improve hair regrowth in mice, comparable to the effects of 3% Minoxidil, potentially due to their anti-inflammatory properties.
May 2011 in “Utrecht University Repository (Utrecht University)” This study found no statistically significant difference in the severity of insect bite hypersensitivity symptoms between horses receiving a nicotinamide supplement and those receiving a placebo.