Effect of Topical Naringenin and Its Combination With Minoxidil on Enhancing Hair Growth in a Mouse Model

    November 2023 in “ PubMed
    Nooralhuda Khayoon, Sarmad Nory Gany, Julfikar Haider, Ahmed Al Mudhafar
    Image of study
    TLDR Naringenin and its combination with minoxidil significantly improved hair growth in mice.
    The study investigated the efficacy of naringenin (NAR), a compound with antioxidant and anti-inflammatory properties, in reducing hair loss. The experiment involved 24 adult Wistar Albino mice, divided into four groups of six. The groups were treated with ethanol alcohol, minoxidil (5%), 0.5% naringenin, and a combination of naringenin and minoxidil. The treatment groups showed significantly higher total antioxidant capacity in tissue levels and increased serum levels of vascular endothelial growth factor compared to the control group. There were no significant differences in keratinocyte growth factor tissue levels between the treatment and control groups. However, the medication significantly increased hair growth, hair follicle diameter expansion, and hair follicle quantity compared to the control group. The results suggest that NAR significantly reduced hair loss in adult male mice.
    Discuss this study in the Community →

    Research cited in this study

    16 / 16 results

    Related Community Posts Join

    1 / 1 results

      community Oral Minoxidil and Grapefruit Juice

      in Research/Science  96 upvotes 1 year ago
      The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

    Related Research

    9 / 9 results