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    Glossary Non-Lesional Control

    sample from unaffected area used for comparison in studies

    Non-Lesional Control (NLC) refers to a sample of tissue or skin that is taken from an area not affected by a disease or condition, used as a baseline or comparison in scientific studies. In the context of hair and alopecia research, NLC samples are often compared to lesional samples (affected areas) to understand the differences and underlying mechanisms of the condition.

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    Research 30 of 1000+

    1. 1370 MTORC1 activity is increased in the skin of acne patients and is suppressed with isotretinoin treatment Journal of Investigative Dermatology · 2023
    2. 1318 Both lesional and non-lesional skin from acne patients shows robust IL-17-skewing and upregulation of antimicrobial peptides Journal of Investigative Dermatology · 2018
    3. Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures Genomics · 2010 · 61 citations
    4. The Follicular Skin Microbiome in Patients With Hidradenitis Suppurativa and Healthy Controls JAMA dermatology · 2017 · 220 citations
    5. 원저 : 안드로겐성 탈모증의 병변부와 비병변부에서 안드로겐 수용체의 면역조직화학적 표현 비교 대한피부과학회지 · 1994
    6. Mechanistic target of rapamycin (mTOR) expression is increased in acne patients' skin Experimental Dermatology · 2015 · 74 citations
    7. Narrowband UVB treatment induces expression of WNT7B, WNT10B and TCF7L2 in psoriasis skin Archives of Dermatological Research · 2019 · 5 citations
    8. Gene Expression of CD70 and CD27 Is Increased in Alopecia Areata Lesions and Associated with Disease Severity and Activity Dermatology Research and Practice · 2022 · 1 citations
    9. Investigation of hair shaft in seborrheic dermatitis using atomic force microscopy Skin Research and Technology · 2011 · 17 citations
    10. 058 The pattern of Fas and Fas ligand expression in alopecia areata Journal of Investigative Dermatology · 2024
    11. Differential expression of mTOR signaling pathway proteins in lichen planopilaris and frontal fibrosing alopecia Acta histochemica · 2018 · 5 citations
    12. Associations Between Skin Microbiome and Metabolome in the Pathogenesis of Atopic Dermatitis Patients With Scalp Involvement Allergy Asthma and Immunology Research · 2024 · 3 citations
    13. 030 Impaired Glutathione Synthesis in Hair Follicle Stem Cell Niches in Alopecia Areata Journal of Investigative Dermatology · 2025
    14. 1322 Molecular profiling of frontal fibrosing alopecia (FFA) reveals TH1 and JAK-STAT up-regulation with no suppression of hair keratins Journal of Investigative Dermatology · 2018 · 2 citations
    15. 1315 An Integrated model of alopecia areata biomarkers highlights both Th1/Th2 upregulation, with stronger correlations between Th2 activation and disease severity Journal of Investigative Dermatology · 2018
    16. 1406 Environmental pathobiology of frontal fibrosing alopecia (FFA): A link between linalool sensitization and FFA development Journal of Investigative Dermatology · 2023
    17. Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata Scientific Reports · 2018 · 19 citations
    18. Evaluation of platelet-rich plasma on hair regrowth and lesional T-cell cytokine expression in alopecia areata: A randomized observer-blinded, placebo-controlled, split-head pilot study Journal of The American Academy of Dermatology · 2020 · 9 citations
    19. Female type of adult acne: Physiological and psychological considerations and management Journal der Deutschen Dermatologischen Gesellschaft · 2018 · 42 citations
    20. The role of hsa‐miR‐193a‐5p as an important factor for control of inositol in alopecia areata Skin Research and Technology · 2024
    21. 1311 Efficacy of topical tofacitinib in promoting hair growth in non-scarring alopecia Journal of Investigative Dermatology · 2018
    22. COMPARATIVE STUDY BETWEEN INTRALESIONAL INJECTION OF PLATELET RICH PLASMA AND INTRA LESIONAL TRIAMCINOLONE FOR THE TREATMENT OF ALOPECIA AREATA Journal of Ayub Medical College Abbottabad · 2022
    23. Meta-Analysis of Gene Expression Reveals the Core Transcriptomic Profile of Lesional Scalp in Alopecia Areata Dermatology and Therapy · 2025
    24. Platelet-Rich Plasma in the Management of Alopecia: A Systematic Review and Meta-Analysis of Clinical Evidence Dermatology and Therapy · 2025
    25. Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus Veterinary sciences · 2024
    26. Female Adolescent Hair Disorders Journal of Pediatric and Adolescent Gynecology · 2009 · 20 citations
    27. Hair and nail involvement in lupus erythematosus Clinics in Dermatology · 2004 · 18 citations
    28. Transverse Needling After Autologous Mini-Punch Grafts Improves Repigmentation in Stable Non-Segmental Vitiligo Clinical Cosmetic and Investigational Dermatology · 2021 · 10 citations
    29. Ottawa, Ontario, Canada, February 13–16, 2013 The Journal of Rheumatology · 2013 · 4 citations
    30. Dermatite atópica em uma cadela: Caso clínico Pubvet · 2019