5 citations,
January 2009 in “Dermato-endocrinology” ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
4 citations,
June 2021 in “Dermatology” Scientists created a 3D skin model to study a chronic skin disease and test treatments.
4 citations,
November 2017 in “Scientific Reports” The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
4 citations,
October 2007 in “Dermatologic Clinics” Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
3 citations,
February 2021 in “Medical journal, Armed Forces India” Combination therapy promotes better hair growth and density.
3 citations,
June 2017 in “International Journal of Radiation Biology” Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
1 citations,
November 2020 in “Biochemical Society transactions” Different types of skin stem cells can change and adapt, which is important for developing new treatments.
1 citations,
March 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” The hair treatment made hair grow faster and thicker and strengthened the hair roots.
1 citations,
July 2016 in “Elsevier eBooks” Understanding skin structure and development helps diagnose and treat skin disorders.
1 citations,
December 2015 in “The Egyptian Journal of Histology” Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.
August 2023 in “Scientific reports” Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
June 2019 in “Pediatric Dermatology” Alopecia in patients with epidermolysis bullosa varies in severity and is often caused by skin blistering or trauma.
May 2018 in “Journal of Investigative Dermatology” DNMT3A is crucial for healthy skin and hair growth.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” M2 macrophages help hair regrowth in wounds by making growth factors.
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
July 2011 in “British Journal of Dermatology” Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.
April 2018 in “Journal of Investigative Dermatology” Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
January 2023 in “Indian dermatology online journal” A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.
35 citations,
August 2009 in “Differentiation” Desmoglein 4 is controlled by specific proteins that affect hair growth.
12 citations,
October 2018 in “Biotechnology reports” Recombinant keratin K31 makes damaged hair thicker, stronger, and straighter.
165 citations,
December 2004 in “Differentiation” BMP signaling is crucial for skin and hair growth.
53 citations,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” KAP genes show significant genetic variability, but its impact on hair traits is unclear.
1 citations,
August 2024 in “Animals” KRT85 gene variations can help improve wool traits in sheep through selective breeding.
98 citations,
May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
85 citations,
January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
84 citations,
December 2008 in “Developmental biology” Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
51 citations,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.