37 citations,
February 2014 in “Journal of Dermatology” Valproic acid increases hair count in men with hair loss.
22 citations,
April 2006 in “Journal of Dermatological Science” Vitamin C derivative increases versican in cells, potentially aiding hair growth.
18 citations,
February 2018 in “International Journal of Molecular Sciences” PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
12 citations,
May 2003 in “Journal of dermatological science” Hsc70 protein may influence hair growth by responding to androgens.
11 citations,
May 2016 in “Naunyn-Schmiedeberg's Archives of Pharmacology” A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.
6 citations,
January 2016 in “Annals of Dermatology” Human hair contains more glycosaminoglycans in children than adults, and these compounds decrease with age, possibly affecting hair thickness.
2 citations,
November 2008 in “Medical Hypotheses” VEGF and its receptor might cause hair loss.
October 2023 in “Scientific reports” Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
174 citations,
November 2002 in “Expert Reviews in Molecular Medicine” Hair loss needs more research for better treatments.
26 citations,
January 2013 in “BMJ Open” Severe baldness on the top of the head is linked to a higher chance of heart disease, especially in men under 60.
23 citations,
January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
22 citations,
August 2011 in “Journal of Supercritical Fluids” Rice bran extract might help prevent hair loss.
12 citations,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
11 citations,
July 2008 in “Facial Plastic Surgery Clinics of North America” Hair restoration surgery redistributes existing hair to achieve a natural look, with visible regrowth in 3-4 months and rare complications, mostly aesthetic.
10 citations,
June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
10 citations,
January 2009 in “Elsevier eBooks” Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
7 citations,
September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences” Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
2 citations,
January 2018 in “Dermatology Review/Przegląd Dermatologiczny” Use trichoscopy to diagnose hair loss; treat with minoxidil, finasteride, or dutasteride; consider platelet-rich plasma and spironolactone.
1 citations,
January 2009 in “CRC Press eBooks” Finasteride increases hair count and improves hair growth with low risk of side effects.
299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
143 citations,
October 1996 in “Dermatologic Clinics” Too much androgen can cause hair loss; finasteride may help.
129 citations,
October 2000 in “British Journal of Dermatology” Finasteride helps increase hair growth in men with hair loss.
101 citations,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
97 citations,
March 2009 in “Dermato-endocrinology” Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
95 citations,
May 2012 in “British Journal of Dermatology” Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
80 citations,
August 2002 in “Journal of Dermatology” Best hair growth results from combining finasteride and minoxidil.
78 citations,
February 2004 in “British Journal of Dermatology” Melatonin helps hair growth in women with hair loss.
48 citations,
October 2014 in “International Journal of Cardiology” People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
47 citations,
October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
44 citations,
June 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.