research Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
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research Estrogens and the Skin
Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
research Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Toll-Like Receptor Function in Acute Wounds
Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
research Alteration of Skin Properties with Autologous Dermal Fibroblasts
Using your own skin cells can help repair aging skin and promote hair growth.
research Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans
Different parts of the body's fat tissue have unique cell types and characteristics, which could help treat chronic wounds.
research Tissue Expanders for Hair Restoration in the Scalp: Overexpansion Does Matter
Tissue expansion is a safe and effective method for scalp hair restoration with high success and patient satisfaction.
research Accelerated Wound Healing Using Nanoparticles
Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice: A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
research Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures
Skin cysts might help advance stem cell treatments to repair skin.
research Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair
Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.
research Design of an Artificial Skin. IV. Use of Island Graft to Isolate Organ Regeneration from Scar Synthesis and Other Processes Leading to Skin Wound Closure
Island grafts can help study skin regeneration separately from other healing processes.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
research Skin Aging as a Mechanical Phenomenon: The Main Weak Links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
research Emerging Nonmetabolic Functions of Skin Fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Cocktail Cell-Reprogrammed Hydrogel Microspheres Achieving Scarless Hair Follicle Regeneration
New microspheres help heal skin wounds and regrow hair without scarring.
research Micropatterned Dermal–Epidermal Regeneration Matrices Create Functional Niches That Enhance Epidermal Morphogenesis
The new matrix improves skin regeneration and graft performance.
research Wound Healing With Topical BRAF Inhibitor Therapy in a Diabetic Model Suggests Tissue Regenerative Effects
A topical BRAF inhibitor, vemurafenib, can speed up wound healing and promote hair growth, especially in diabetic patients.
research Platelet-Rich Plasma: Principles and Applications in Plastic Surgery
Platelet-rich plasma is beneficial in various plastic surgery applications, but more research is needed to standardize its use.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Promoted Growth of Murine Hair Follicles by Controlled Release of Growth Factors from Biodegradable Hydrogel
Using hydrogels to slowly release growth factors can effectively boost hair growth in mice.
research Diabetex: A Novel Approach for Diabetic Wound Healing
Diabetex improves diabetic wound healing better than metformin.
research Activating an Adaptive Immune Response from a Hydrogel Scaffold Imparts Regenerative Wound Healing
Hydrogel scaffolds can help wounds heal better and grow hair.
research An ERK-Dependent Molecular Switch Antagonizes Fibrosis and Promotes Regeneration in Spiny Mice
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
research Skin Organoids: A New Human Model for Developmental and Translational Research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research Skin Graft Harvesting and Donor Site Selection
The document concludes that skin grafts are essential for repairing tissue loss, with various types available and ongoing research into substitutes to improve outcomes and reduce donor site issues.
research The Human Tri-Peptide GHK and Tissue Remodeling
The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
research Spontaneous Hair Follicle Germ Formation In Vitro, Enabling The Large-Scale Production Of HFGs For Regenerative Medicine
Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.