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The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

Teriflunomide effectively reduces relapse rates and disease progression in multiple sclerosis but is not safe for use during pregnancy.

Tofacitinib helped regrow hair in patients with alopecia, with few side effects.

Anti-SSB antibodies are useful for diagnosing systemic lupus erythematosus and are linked to specific symptoms.

Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.

Genetic testing is crucial before giving azathioprine to avoid severe side effects.

A 9-year-old girl with a healthy immune system was successfully treated for a severe fungal scalp infection caused by Microsporum audouinii.

Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

In September 2016, there were major advancements and promising clinical trials in stem cell research and regenerative medicine.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.

Topical corticosteroids are the best initial treatment for children's alopecia areata.

Thallium, mercury, selenium, and colchicine strongly cause hair loss.

Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.

Ruxolitinib effectively and safely regrows hair in alopecia patients.

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

Baricitinib improved severe hair loss in adults over 52 weeks and was safe to use.

Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.

Preventive measures and effective management are crucial for reducing skin side effects in cancer treatment.

Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.

Low dose valproate in epileptic children mainly causes weight gain and other non-life-threatening side effects.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Hair microscopy is a simple and cost-effective method to help diagnose systemic diseases in children.

JAK-inhibitors for alopecia areata are generally safe with mostly mild side effects and a low rate of treatment withdrawal.

Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.

Paclitaxel is an effective cancer drug with side effects and potential new uses beyond cancer.

Certain genetic markers linked to wool quality in Rambouillet sheep were identified, which can guide better breeding choices.

Ocoxin improves quality of life for advanced ovarian cancer patients on chemotherapy.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.