Specificity of Anti-SSB as a Diagnostic Marker for the Classification of Systemic Lupus Erythematosus

    April 2013 in “ Experimental and Therapeutic Medicine ”
    Rao Li, Guiyan Liu, LI Chunfen, Yajuan Li, Zhiguo Wang, ZIJIAO ZHOU, Sheng-quan Tong, Xianming Wu
    TLDR Anti-SSB antibodies are useful for diagnosing systemic lupus erythematosus and are linked to specific symptoms.
    The study investigated the diagnostic value of anti-SSB antibodies in 74 SLE patients, finding them in 25.7% of SLE cases and 3.3% of controls, with a specificity of 96.7%. Anti-SSB-positive SLE patients exhibited higher rates of cheek erythema, alopecia, serositis, secondary Sjögren’s syndrome, leukocytopenia, elevated IgG, and anti-SSA60 or anti-SSA52 antibodies. The study concluded that anti-SSB antibodies are significant for diagnosing SLE and are linked to specific clinical features, recommending further molecular studies to confirm these results.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Why I really believe the tension theory is the cause of MPB

      in Research/Science  70 upvotes 3 years ago
      The conversation discusses the tension theory as a cause of male pattern baldness (MPB), suggesting that scalp tension and reduced subcutaneous fat layer contribute to hair loss. Treatments mentioned include Minoxidil, finasteride, microneedling, scalp massages, and Botox.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Is microneedling supposed to be a blood bath? 1mm dermastamp

      in Microneedling  41 upvotes 8 months ago
      The conversation is about someone experiencing a lot of bleeding from using a 1.0mm microneedling device for hair loss treatment and asking if it's normal. Various users suggest that the bleeding is excessive and recommend using shorter needles or less pressure, while others share their own microneedling practices with different needle lengths and no bleeding.

      community Comprehensive Microneedling Guide

      in Microneedling  293 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

    Related Research

    1 / 1 results