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Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.

Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

New drugs for heart disease may be developed from molecules secreted by stem cells.

High-dose radiation speeds up aging in skin stem cells.

Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.

iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.

New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Collagen-enhanced mesenchymal stem cells significantly improve skin wound healing.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.

Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.

MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.

Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Fetal skin has unique immune cells different from adult skin.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

Host cells are crucial for the maturation of reconstructed hair follicles.