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January 2020 in “International Journal of Trichology” This study found that patients with early onset androgenetic alopecia had significantly higher levels of the biomarker YKL-40, suggesting a link to both the condition's pathogenesis and related metabolic syndrome.
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December 2017 This review found that androgenetic alopecia may be linked to increased cardiovascular and metabolic risks, but the relationship is not yet fully understood, and specific guidelines for cardiovascular disease detection and prevention in these patients have not been established.
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July 2017 in “Clinical research in dermatology” This review covers the pathogenesis, diagnosis, and potential new treatments for androgenetic alopecia but reports no new clinical findings, highlighting an ongoing need for effective therapies.
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January 2017 in “International Journal of Research in Medical Sciences” This study found that metabolic syndrome was 4.6 times more common in patients with androgenetic alopecia than in controls, particularly among those with severe grades, suggesting a higher risk of cardiovascular diseases.
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January 2015 in “Journal of Dermatology and Venereology” This study concluded that androgenetic alopecia may predict ischemic heart disease, and recommended that patients with AGA be screened for coronary artery disease.
March 2026 in “Dermatology Online Journal” In this study, androgenetic alopecia was linked to a higher likelihood of hyperlipidemia in both men and women and obesity in women, highlighting it as a potential marker for cardiometabolic risk.
February 2026 in “International Journal of Molecular Sciences” In this study, researchers identified 47 proteins associated with male pattern baldness severity and prioritized five candidate genes, including druggable CD38, suggesting new non-hormonal targets for therapeutic development.
January 2026 in “BMC Public Health” This meta-analysis found that several factors are significantly associated with the presence and progression of androgenetic alopecia, including family history, smoking, alcohol consumption, poor sleep quality, being overweight, hypertension in men, insulin resistance, and high fasting insulin levels.
January 2026 in “Aesthetic Plastic Surgery” This study found that disease duration was the only independent risk factor for increased severity of female pattern hair loss, rather than elements, vitamins, or hormones.
January 2026 in “International Journal of Molecular Sciences” Understanding molecular signals and genetics is key to improving hair regeneration therapies.
January 2026 in “Journal of Clinical Medicine” This review identified significant associations between glucose dysregulation and various dermatological conditions like psoriasis and acne, suggesting that dietary interventions and probiotics may help manage related inflammation, highlighting the need for holistic treatment approaches for insulin resistance and metabolic syndrome.
November 2025 in “Biomedicines” This review highlights hypochlorous acid's potential benefits in various medical fields due to its antimicrobial and healing properties but stresses the need for further research on dosing and product development.
November 2025 in “Cosmetics” This study found that of the many ingredients advertised in shampoos as effective against hair loss, only caffeine, adenosine, placental proteins, and melatonin have limited clinical evidence supporting their efficacy, with most claimed active ingredients lacking any trial-based validation.
July 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found a bidirectional causal association between major depression disorder and alopecia areata, but no association between mental disorders and androgenetic alopecia, suggesting a focus on mental health strategies for alopecia areata management.
June 2025 in “Cancer Management and Research” This study found that scalp cooling resulted in visible hair retention in 53% of breast cancer patients undergoing Epirubicin/Cyclophosphamide and Paclitaxel treatment, with factors like hair bulb diameter, shaft diameter, and anagen rate significantly predicting outcomes.
January 2025 in “International Journal of Trichology” This study reported that among young males with early-onset androgenetic alopecia, there is a high prevalence of metabolic syndrome, particularly in those with severe hair loss, indicating a potential need for early screening and lifestyle changes to reduce cardiovascular risks.
October 2024 in “Cosmetics” In this study, subthermal RF-CRET currents were found to alter key molecular mechanisms in dermal papilla cells, promoting proliferation and survival while enhancing markers associated with hair growth and maintenance, suggesting potential benefits for hair regeneration.
October 2024 in “Journal of College of Physicians And Surgeons Pakistan” In this study, researchers observed an association between androgenetic alopecia and metabolic syndrome, suggesting potential benefits in screening individuals with this type of hair loss for metabolic issues to prevent further health complications.
August 2024 in “Clinical Cosmetic and Investigational Dermatology” This study investigates the potential causal relationship between hypothyroidism and hair loss conditions like alopecia areata and androgenetic alopecia, noting that previous studies have reported inconsistent findings. Results are not yet detailed.
July 2024 in “Deleted Journal” This study found that using PRP with the FUE method of hair restoration led to better graft survival, aesthetic outcomes, and patient satisfaction compared to not using PRP.
May 2024 in “Indian Journal of Dermatology” In this review, an association was reported between early-onset androgenetic alopecia and several health conditions like obesity and cardiovascular disease, with genetic and therapeutic research ongoing to improve treatment.
May 2024 in “International Journal of Nanomedicine” This review examined the diverse therapeutic potentials of cannabinoids, highlighting their applications in pain, neurological, and cancer treatments, and emphasized the benefits of biodegradable polymers in improving drug delivery; however, further clinical trials are needed to fully explore these potentials.
April 2024 in “International journal of molecular sciences” This narrative review discusses the promising role of photobiomodulation in dermatology, emphasizing its non-invasive nature and potential benefits, but acknowledges the need for further research to establish standard protocols.
In this study, a case was reported where oral Minoxidil led to severe ocular complications, specifically Central Retinal Vein Occlusion and Cilioretinal Artery Occlusion, resulting in sudden vision loss which improved upon discontinuation.
February 2024 in “Medicina-lithuania” This narrative review explores how obesity, related diseases, and bariatric surgery can impact hair health and the hair development cycle, highlighting potential effects such as hair thinning and telogen effluvium.
February 2024 in “Clinical, Cosmetic and Investigational Dermatology” This study reports a solid causal relationship between increased serum levels of ApoB, LDL, and VLDL and an elevated risk of androgenic alopecia.
This case study observed that individualized homeopathic treatment, particularly Lycopodium clavatum, appeared useful in managing androgenetic alopecia comorbid with iron deficiency anemia and COVID-19 in a 17-year-old male, though the authors emphasize the need for larger studies to confirm these findings.
November 2023 in “Brain Sciences” This study investigated medications potentially linked to male-factor infertility using the FDA Adverse Event Reporting System and found that finasteride, testosterone, valproate, and other drugs showed significant disproportionate reporting of infertility cases, highlighting a potential under-reporting issue to regulatory bodies.
November 2023 in “Heliyon” This article reports a case of herpes zoster ophthalmicus following platelet-rich plasma treatment for androgenic alopecia and emphasizes adhering to guidelines to ensure safe outcomes.