Unlocking the Power of Light on the Skin: A Comprehensive Review on Photobiomodulation

April 2024 in “ International journal of molecular sciences ”

María Luisa Hernández‐Bule, Jorge Naharro-Rodríguez, Stefano Bacci, M. Fernández‐Guarino

photobiomodulation PBM light-based treatment dermatology cellular chromophores signaling pathways clinical trials experimental studies non-invasive therapeutic option light therapy skin treatment

TLDR Light-based treatment, Photobiomodulation, shows promise for non-invasive skin therapy with few side effects.

Photobiomodulation (PBM) is a non-invasive therapy using red and near-infrared light to treat various dermatologic conditions, including acne, wound healing, skin rejuvenation, and hair disorders like androgenic alopecia and alopecia areata. PBM prolongs the anagen phase of hair growth, increases hair density and length, and reduces inflammatory lesions in acne by absorbing photons through mitochondrial cytochrome C oxidase, promoting cellular processes without thermal damage. Despite promising results and a good safety profile, standardized treatment protocols are lacking, necessitating further research and collaboration between dermatologists and basic researchers.

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