Insulin Resistance, Metabolic Syndrome, And Inflammatory Skin Disease

The review examines the link between insulin resistance (IR), metabolic syndrome (MetS), and various inflammatory skin diseases, including psoriasis, acne, acanthosis nigricans, seborrheic dermatitis, hidradenitis suppurativa, and androgenetic alopecia (AGA). It highlights that elevated insulin levels and inflammatory markers are associated with the severity of these conditions. The review suggests that dietary interventions and probiotics may help modulate inflammation and improve metabolic health. A study involving 13,830 participants found a higher prevalence of MetS in patients with these skin conditions, with an odds ratio of 3.28. The document underscores the importance of a holistic treatment approach, including glucose control and lifestyle modifications, to improve patient outcomes and reduce complications related to IR and MetS. Further research is needed to refine these integrative strategies and evaluate their clinical effectiveness.