Factors Associated With the Severity of Female Pattern Hair Loss: A Retrospective Study

January 2026 in “ Aesthetic Plastic Surgery ”

Meiling Jian, Dan Zhang, Xingang Fu, Yuheng Cheng, Xiaoyu Sun, Zhibin Wang, Lin Li

female pattern hair loss FPHL selenium zinc vitamin B9 testosterone

From the encyclopedia

Studysummary This study found that disease duration was the only independent risk factor for increased severity of female pattern hair loss, rather than elements, vitamins, or hormones.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This retrospective study of 289 patients with female pattern hair loss (FPHL) identified that the severity of FPHL is associated with the duration of the condition, with more severe cases (F2/3) being significantly older and having a longer duration than less severe cases (F1). Although lower levels of selenium, zinc, vitamin B9, and testosterone were noted in the more severe group, these were not independent risk factors after adjusting for demographic characteristics. The study concludes that elements, vitamins, and hormones do not predict FPHL severity, suggesting the need for larger prospective cohort studies to confirm these findings.

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