The Impact of Exogenous Vitamin D on Thyroid Autoimmunity in Euthyroid Men with Autoimmune Thyroiditis and Early-Onset Androgenic Alopecia

    June 2021 in “ Pharmacological Reports ”
    Robert Krysiak, Karolina Kowalcze, Bogusław Okopień
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    TLDR Vitamin D may help reduce antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but has no significant impact on thyroid function.
    A study of 67 young men, 25 of whom had early-onset androgenic alopecia, found that exogenous vitamin D supplementation did not have a significant impact on thyroid autoimmunity or thyroid function in euthyroid men with autoimmune thyroiditis and early-onset androgenic alopecia. However, vitamin D may have a positive impact on reducing antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but the effect is more significant in those without alopecia. Additionally, vitamin D increased SPINA-GT only in those with alopecia. The study suggests that men with early-onset androgenic alopecia and male siblings of women with PCOS have lower levels of vitamin D, and women with PCOS have a higher prevalence of autoimmune thyroiditis and elevated thyroid antibodies.
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