TLDR Men with early balding may have hormonal imbalances similar to women with PCOS and could benefit from similar treatments.
The document discusses the concept of Polycystic Ovary Syndrome (PCOS) in men, suggesting that the syndrome's manifestations are not limited to women. It references a study by Sanke et al. which found that men with early androgenetic alopecia have hormonal profiles similar to women with PCOS. The authors, Cohen and Kurzrock, had previously hypothesized nearly a decade before that male relatives of women with PCOS might also suffer from related conditions such as cardiovascular disease, diabetes mellitus, insulin resistance, and obesity. They recommended that both men and women who are first-degree relatives of patients with PCOS be evaluated for phenotypic features of PCOS and biochemical evidence of hyperinsulinemia and hyperandrogenism. The authors also suggested that treatment for the metabolic symptoms and complications associated with PCOS could be beneficial regardless of gender. The recent findings by Sanke et al. confirm the authors' hypothesis of PCOS in men.
258 citations,
July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
47 citations,
June 2016 in “JAMA Dermatology” Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.
18 citations,
April 2016 in “Endocrinology and Metabolism Clinics of North America” The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.
30 citations,
September 2017 in “Clinics in Dermatology” Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
3 citations,
May 2021 in “Molecules” Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.
May 2022 in “Maǧallaẗ Buḥūṯ Al-Tarbiyyaẗ Al-Nawʿiyyaẗ (Print)” Eating a high inositol diet significantly improves insulin resistance and hormone levels in women with PCOS.
January 2019 in “Obstetrics & Gynecology International Journal” Hormonal changes and conditions like polycystic ovarian syndrome are major causes of adult acne in women, with varying prevalence among different ethnicities.
March 2017 in “InTech eBooks” Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.